Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"SGK"”.
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Genetic Factors and Dietary Salt Intake as Determinants of Blood Pressure and Risk of Primary Hypertension
… and glucocorticoid regulated kinase 1 gene (SGK-1)) or both (Neural precursor cell Expressed Developmentally Down regulated 4 like gene (NEDD4L)) (study III-V); (iii) investigate the role of dietary salt restriction on BP as well as to explore the possibility to predict this BP change by …
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SGK3 activity and regulation in PI3K-Akt pathway inhibitor resistance in breast cancer
… is heavily studied, however the highly related SGK family of protein kinases have recently been identified as driving cancer cell growth in certain contexts. In particular, my research interest and the focus of this thesis is the role these kinases, in particular SGK3, has in resistance to Class …
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Understanding Potassium Homeostasis Using Human and Mouse Genetic Models
… activation of Akt1/SGK can phosphorylate threonin 58 of WNK1 and thus inhibits ROMK current in cultured cells. In addition to full-length WNK1, the kinase-deficient WNK1 isoform, kidney-specific WNK1 (KS-WNK1), also participates in the regulation of renal sodium and …
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Exploring the Glucocorticoid Actions of 1α-Hydroxycorticosterone (1α-OH-B) in the Elasmobranch Fishes
… serum- and glucocorticoid- inducible kinase 1 (SGK1). <em>SGK1 </em>mRNA abundance was upregulated in red blood cells incubated with 1α-OH-B. The results of these studies support the putative GC actions of 1α-OH-B, including the correlation of 1α-OH-B with basal glucose <em>in vivo </em>and the …