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Showing 1 to 1 of 1 for “"SGI-1776"”.
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Pim Kinase Inhibition: Single Agent and Combination Approaches In B-Cell Lymphoma
… it negatively correlates with patient outcome. SGI-1776 is a small molecule inhibitor selective for Pim-1/-3. We hypothesize that SGI-1776 treatment in MCL will inhibit Pim kinase function, and inhibition of downstream substrates phosphorylation will disrupt transcriptional, translational, and …