Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"SF1+"”.
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Transcriptional regulation of the Human Zfm1/Sf1 Gene
Das erste Ziel der hier vorgelegten Arbeit war zu untersuchen, ob die Zytokine IL-1β/TNFα und/oder der Wachstumsfaktor PDGF, ähnlich wie in glatten Gefäßmuskelzellen (GMZ) der Ratte, auch in humanen GMZ die Expression des Gens für den transkriptionellen Repressor Zfm1 hemmen und so die …
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Identifying the mechanism critical for proliferation, apoptosis, and cell-cell interaction in the development of mouse adrenals and gonads
… that consists of Steroidogenic factor 1 (SF1)-positive precursor cells. SF1 not only defines the steroidogenic lineages in these organs, but also controls their differentiation. In this thesis project, I used Sf1/Cre transgenic mice to generate different types of knockout models to study …
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Essential Protein Factors in pre-mRNA splicing : A Structural Study by Nuclear Magnetic Resonance Spectroscopy
… between the essential splicing factors SF1 and U2 auxiliary factor 2 (U2AF) is provided. This interaction involves the third RNA recognition motif (RRM3) of the large subunit of U2AF (U2AF65) and the N-terminal 25 residues of SF1. The structure of RRM3 exhibits the classical RNP-type …
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Role of the ventromedial hypothalamus in control of innate defensive behaviours
… activating the VMH output neurons (SF1+ cells) can produce a variety of different behaviours, from immobility to escape, depending on the intensity of activation. During my PhD I used a variety of approaches to address the question of the function of the VMH in control of defensive …
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Respostas hidrológicas e meio físico: uma análise comparativa em duas sub-bacias da Unidade de Planejamento e Gestão de Recursos Hídricos do Alto São Francisco, Minas Gerais (UPGRH-SF1) (MG)
… Recursos Hídricos do Alto São Francisco (UPGRH-SF1), que drenam substratos geológicos diferentes. Com os dados hidrológicos foram construídos diagramas de variação anual de vazão (hidrogramas) e curvas de permanência, ao longo de séries históricas em cada uma das sub-bacias, a partir das quais …
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The role of beta-catenin in the development of fetal ovary and female germ cells
… specifically in the steroidogenic factor 1 (SF1)-positive population of somatic cells of the fetal gonads. In the absence of β-catenin, fetal testis developed normally whereas unique phenotypes appeared during the development of ovary. These phenotypes included formation of testis-specific …
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Exploring combined effects of arsenic and selenium exposure on larval zebrafish (Danio rerio)
… (Mn-SOD, gpx), neurogenesis (ngn1, hucs, bdnf, sf1), dopaminergic (Sncgb, otpa, robo2, th1), serotonergic (pet1, tph2), and motor neuron (pax2a) was observed following arsenic exposure. At the same time, co-treatment with As + Se 25 µg/L partially restored nrf2a expression (p < 0.05). These …
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Investigating the maintenance of the mouse definitive adrenal cortex
… It has been reported that steroidogenic factor (Sf1) can promote the differentiation of MSCs into steroidogenic cells, and Shh plays an important role in Sf1 expression and the consequent adrenal development. However, Shh treatment failed to achieve transformation of mesenchymal cells into …
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Computer-Assisted Image Analysis of Human Ovarian Follicles: Imaging Physiologic Selection
… of human dominant (DF) and 1st subordinate (SF1) ovarian follicles during natural menstrual cycles and following discontinuation of conventional and continuous oral contraceptives (OC). We utilized sophisticated computer algorithms to elucidate an association between image attributes and …
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Fluoride-salt-cooled high-temperature test reactor thermal-hydraulic licensing and uncertainty propagation analysis
… reactors currently considered, the Chinese TMSR-SF1 pebble bed design and MIT's Transportable FHR prismatic core design; two candidate coolants, flibe (LiF-BeF2) and nafzirf (NaF-ZrF4); and forced flow and natural circulation conditions to compare operating regions and LSSS power (maximum power …
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Functional Investigation of RNA Viral Helicases as Molecular Targets for the Discovery of Novel Antiviral Agents
… the NS3 of WNV. Despite belonging to SF2 and SF1, respectively, the two proteins have strong similarities: both are non-ring forming helicases with core RecA-like domains; they share conserved motifs across the helicases and possess similar NTPase, helicase, and RTPase activities. SARS-CoV-2 …