NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 5 of 5 for “"SETD2"”.

  1. The Regulation of Cellular Iron Metabolism

    Martinelli, AnthonyUniversity of Cambridge2023

    … genes without known links to iron homeostasis. SETD2, a histone methyltransferase, was a top hit in the screen, and provides the first example of a chromatin modifying enzyme as a mediator of iron levels. SETD2 depletion leads to an increase in the levels of the cargo receptor NCOA4, responsible …

    cambridge Repository record

  2. Paraspeckle protein NONO regulates active chromatin by allosterically stimulating NSD1

    Hsu, Chen-IVirginia Tech2025

    … system for expressing full-length (FL) NSD1 and SETD2. By isolating monoclonal baculovirus clones and optimizing a single-step FLAG purification protocol, I obtained highly pure recombinant proteins suitable for enzymatic assays. Importantly, both enzymes retained catalytic activities, …

    vt Repository record

  3. Regulation of the histone H3K36 methyltransferase Set2 by the histone chaperone Spt6

    Elchert, AlexandraHarvard University Graduate School of Arts and Sciences2026

    … of the mammalian H3K36 methyltransferase SETD2. Several studies have shown that Set2 activity in vivo requires the histone chaperone Spt6. Genetic studies in yeast suggested that Spt6 regulation occurs via controlling a Set2 autoinhibitory domain (AID) and recent structural studies of …

    harvard Repository record

  4. Using Tissue Morphology to Infer Intra-Tumor Variation in Molecular State and Response

    Acosta, Paul Humberto2026

    … variation in key driver genes, BAP1, PBRM1, and SETD2, can be inferred purely from the analysis of histopathology slides. Our work demonstrated for the first time that the morphology-genetics relationship was powerful enough for inference of intra-tumor heterogeneity in driver mutation status …

    utswmed Repository record

  5. Modeling of Cns Cancer With A Focus On The Immune Component

    Zamler, Daniel, <p>0000-0003-0375-8119</p>2023

    … gene, an <em>R1407</em> frameshift in the <em>SETD2</em> gene of the PIK3CA pathway, <em>R462H</em> in the <em>NF2</em> gene, and a <em>I463V</em> mutation in <em>TSC2</em>. Two patients testing positive for epidermal growth factor receptor (EGFR) expression were negative for the EGFRvIII …

    uthsc Repository record