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Showing 1 to 3 of 3 for “"SERCA2a-Expression"”.
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Entwicklung und Erprobung eines in-vitro-Modellsystems zur Untersuchung von lastabhängigen Regulationsvorgängen der myokardialen Genexpression
… den Einfluss von Vor- oder Nachlast auf die Expression von SERCA2a (Sarkoplasmatisches-Retikulum-Calcium-ATPase, Isoform 2A) in isolierten Kaninchen-Herzmuskelpräparaten zu untersuchen. Diese Untersuchungen könnten möglicherweise wichtige Hinweise auf die Regulationsmechanismen der …
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To Phosphorylate or Not to Phosphorylate: The Role of Tropomyosin Phosphorylation in Cardiac Function and Disease
… animals. In TG hearts, there is an increase in SERCA2a expression and an increase in PLN phosphorylation at Ser16. This increase in energetic demand placed on the heart both by the increase in SERCA2a activity coupled with the increased energetic demand that occurs during the onset of cardiac …
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Age-associated changes to calcium handling proteins across the whole heart
… to investigate the effects of ageing on the expression of Ca²⁺ handling proteins. The ageing process was analysed in rats at 6 (young-adult), 12 (adult) and 24 months old (elderly). Heart samples were assessed by western blot, qPCR, immunocytochemistry and electrophysiology. The expression of …