Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"SENP"”.
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Regulation of mGluR7 trafficking by SUMOylatio in neurons
… is prevented by SUMO-specific isopeptidase SENP-1. Furthermore, the SUMOylation of mGluR7mediated by SUMO-1 and SUMO-2/3 is identified in primary cortical neurons. Of particular interest, treatment of mGluR7 with an agonist,L-AP4 leads to a profound decrease of SUMO-1 conjugation of mGluR7, …
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Interplay between collapsin response mediator protein 2 (CRMP2) phosphorylation and sumoylation modulates NaV1.7 trafficking
… with sentrin/SUMO-specific protease SENP1 or SENP2 in wildtype CRMP2-expressing CAD cells decreased Nav1.7 currents. Consistent with reduced current density, biotinylation revealed significant reduction in surface Nav1.7 levels of CAD cells expressing CRMP2-K374A or SENP proteins. …
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A Novel Cardiac Function of Sumo2/3 and Senp5 Dependent Pathway and Its Physiological Impact On Congestive Cardiomyopathy
… Novel cardiac function of SUMO2/3 and SENP5 dependent pathway and its physiologic impact on congestive cardiomyopathy</strong></p> <p>Publication No.___________</p> <p>Eun Young Kim, M.S.</p> <p>Supervisory professor: Robert J. Schwartz, Ph.D.</p> <p>SUMOylation regulates diverse …