Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"SCN2.2"”.
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MECHANISMS OF NEUROPROTECTION IN SCN2.2 CELLS
… A previous study demonstrated that SCN2.2 cells (an immortalized SCN cell line) were resistant to Glu excitotoxicity as compared to GT1-7 neurons (from the neighboring hypothalamus). This thesis explored the cellular mechanisms underlying this endogenous neuroprotection in SCN2.2 …
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The role of serotonin-2C receptors in the rat circadian system.
… expression of various serotonin receptors in the SCN2.2 cell line was compared with that observed in punches of adult rat SCN. The mRNA for 5-HT1B and 5-HT2A receptor was expressed in both the SCN2.2 cell line and the adult rat SCN. However, 5-HT2C receptor mRNA along with 5-HT3 receptor, 5-HT5A …
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Investigation of the SCN 2.2 Cell Line as a Model of the Central Mammalian Circadian Pacemaker
… and human vasoactive intestinal peptide (SCN2.2.vip-luc) promoters. Serumshocked stably transfected SCN 2.2 cell lines displayed near-24 hour rhythms. These rhythms were blocked by inhibition of cGMP-dependent protein kinase (PKG), a known element of several circadian regulatory pathways. …