Global ETD Search
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Showing 1 to 8 of 8 for “"SCH23390"”.
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Antagonizing Dorsal Hippocampal Dopamine D1-type Receptors Affects Social Learning and Social Interactions but not Food Intake in Male and Female Mice
… microinfused the DA D1-type receptor antagonist SCH23390 into the dorsal hippocampus of adult male and female mice. We found that SCH23390 blocked social learning in both male and female mice without influencing total food intake. While there was a sex-specific effect of SCH23390 on certain …
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Investigating the Role of Dopamine D1 Receptor Activation in Overcoming Boundary Conditions for Object Identity and Object Location Memory Malleability
… found that systemic D1 receptor (D1R) antagonist SCH23390 blocked recently encoded and novelty-induced destabilization, and subsequent contextual updating, of relatively remote object identity and object location memories. Systemic D1R agonist SKF38393 was sufficient to induce destabilization of …
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Dopaminergic modulation of risk-based decision making
… or attenuated by co-administration of either D₁ (SCH23390) or D₂ (eticlopride) receptors antagonists. Blockade of either of these receptors alone induced risk aversion. Conversely, stimulation of D₁ (SKF81297) or D₂ (bromocriptine) receptors also increased risky choice. In contrast, activation of …
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Roles of dopamine D1 and D2, opioid and glutamate NMDA receptor signaling in the acquisition and expression of fat- and glucose-conditioned flavor preferences in rats and c-Fos analysis of the dopamine mesotelencephalic and nigrostriatal pathways following intake of sugars and fats in rats
… systemic administration of dopamine (DA) D1 (SCH23390) and D2 (raclopride) antagonists blocked both the acquisition and expression of the orosensory-mediated fructose-CFP and sham sucrose-CFP. DA D1, but not D2, blocked the f/n acquisition, and to a lesser degree, expression, of IG …
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Effect of dopamine on synchronous neuronal oscillations in the globus pallidus-subthalamic nucleus network
… was partially reduced by the D1-like antagonist SCH23390 (2 μM) but not by the D2-like antagonists sulpiride (10 μM) and eticlopride (10 μM). Using whole-recordings, dopamine was shown to induce membrane depolarisation. This depolarisation was caused either by a D1-like receptor mediated increase …
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Aspects of tic like behaviour and serotonergic control
… The selective dopamine D1 receptor antagonists SCH23390 and SCH39166 and dopamine D2 antagonists raclopride and sulpiride had no effect on MK771 induced blinking. The D1 antagonists attenuated fore-paw-tremor and -licking while the D2 antagonists were generally without effect on these …
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STUDIES ON THE ACUTE AND LONG-TERM EFFECTS OF MDMA (3,4- METHYLENEDIOXYMETHAMPHETAMINE)
… antagonist remoxipride but not the Di antagonist SCH23390. Repeated administration of MDMA (2 or 6 doses of 20 mg/kg) to guinea pigs produced an acute hyperthermic response after the first injection but not subsequent injections. A 70% loss of striatal 5-HT and 5-HlAA was found 7 days later, …
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A functional study on novel genes involved in regulating aldosterone secretion in normal human zona glomerulosa and in aldosterone-producing adenomas
… receptor D1R agonist fenoldopam and antagonist SCH23390. IHC showed predominantly intracellular staining for D1R in NEFM-rich ZG-like APAs, but membranous staining in NEFM-poor ZF-like APAs. Aldosterone secretion in response to fenoldopam in primary cells from ZG-like APAs was lower than in …