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Showing 1 to 2 of 2 for “"SCFDia2"”.
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Keeping It Together and Taking It Apart: Structural Investigations of Replisome Complexes Involved in DNA Replication Fork Protection and Termination
… by the termination-specific E3 ubiquitin ligase, SCFDia2.
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In vitro reconstitution of the ubiquitylation and disassembly of the eukaryotic replisome
… disassembly of CMG were known, viz the E3 ligase SCFDia2 and segregase Cdc48, very little was known about the mechanism of CMG disassembly. In the process of learning more about the disassembly of the replicative helicase from chromatin, I reconstituted the ubiquitylation of CMG and thereafter the …