Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 79 for “"SCFA"”.
-
Short-Chain Fatty Acids and Functional Adaptations in the Neonatal Intestine
… absorptive capacity. Short-chain fatty acids (SCFA) are known to enhance this adaptive process in adult animal models, and data from our lab indicates that butyrate (Bu) results in marked changes in glucose transport in the intestine within minutes. We hypothesized that SCFA and Bu would …
-
Dietary Manipulation of Metabolic Function in the Human Gut Microbiome
… processes are myriad, short-chain fatty acid (SCFA) production has been found to be a powerful regulator of inflammation and gastrointestinal (GI) function, and may be central to the link between host and microbiota. Supplementing the diet with microbially accessible carbohydrates, termed …
-
Factors Governing Gastrointestinal Colonization of Candida albicans
… gut microbiota-derived short chain fatty acids (SCFA) directly inhibit C. albicans growth in vitro. SCFA inhibit C. albicans hexose uptake and induce intracellular acidification. In contrast, SCFA promote C. albicans GI colonization resistance in vivo but only when an intact gut microbiome is …
-
Mechanistic insight into the role of dietary fibers and short chain fatty acids in the regulation of metabolism and inflammation in the pig
… and production of short chain fatty acids (SCFA). A series of in vivo experiments were conducted to determine the effects of dietary fiber on pig growth performance and gut microbial community as well as host metabolism. In the first study, a comparison between soluble and insoluble fibers …
-
Short-chain fatty acid production by microbial organisms in model systems assessed by GCMS
<p>Short-chain fatty acids (SCFA) such as butyrate and lactate are the products of colonic bacterial degradation of starch and other carbon sources and are important in human health and disease. Prior work with test tube cultures has provided support for the idea that SCFA production in the …
-
Rewiring anaerobic digestion: production of biofuel intermediates and high-value chemicals from cellulosic wastes
… intermediates, such as short-chain fatty acids (SCFA). The market for these chemicals is growing, and more sustainable practices could replace their current petrochemical-based production. AD for the production of SCFA is an alternative approach with attractive market and economic opportunities. …
-
Effect of proteolytic enzyme and fiber of papaya fruit on human digestive health
… the highest amount of Short Chain Fatty Acids SCFA of the three papaya substrates (unripe, ripe, and processed). SCFA are the most important product of fermentation and are used as indicators of the amount of substrate fermented by microorganisms in the colon. The combination of proteolytic …
-
The effect of butyrate-supplemented total parenteral nutrition on muc2 mRNA and goblet cell chemotypes in a short bowel syndrome neonatal piglet model
… of protective goblet cell chemotypes in the SCFA-supplemented group will be observed, since this group also contains 9 mM butyrate, that butyrate-supplemented TPN will have a greater effect on the small intestine than the large intestine, while butyrate supplementation at 60 mM will have a …
-
Nutritional psychiatry, stress and the microbiota-gut-brain axis: focus on dietary fiber
… to influence gut-brain modules (GBMs) including SCFA synthesis via the gut microbiota, by devising a systematic review protocol followed by its execution and deployment across studies examining the impact of different dietary fiber and compositional alterations with publicly available datasets. …
-
FUNCTIONAL ADAPTATION OF THE RUMINAL EPITHELIUM
Short chain fatty acids (SCFA) synthesized in the rumen from carbohydrate fermentation are an essential energy source for ruminants. Current literature supports that SCFA are absorbed across the rumen epithelium via passive diffusion or protein-mediated transport, however, the rate and degree to …
-
Effect of the maturity at harvest of whole-crop barley and oat on dry matter intake, forage selection, and digestibility when fed to beef cattle
… (6.25; P = 0.016). Total short chain fatty acid (SCFA) concentrations were not affected by harvest maturity (P = 0.36). In Study 2, harvest maturity of whole-crop oat did not affect DMI (P = 0.26; average 8.1 kg/d) or ADG (P = 0.52). There were no effects of harvest maturity of oat forage on total …
-
Characterization of short chain fatty acids in microbial cultures by DART-MS and GC-MS
… carbon sources produces short-chain fatty acids (SCFA) such as butyrate and lactate, which are important in human health and disease. Analysis of the results of mono- and co-cultures in in vitro systems has led to the conclusion that diverse microbial organisms may each contribute in part to the …
-
Optimization and Application of Metabolomic Assays for Analyzing Diet-induced and Gut Microbiota-derived Short-chain Fatty Acids in Mice and Humans
… assay to quantify fecal short chain fatty acids (SCFAs), a byproduct of microbial fermentation in the gut, and to apply this assay to health outcomes of RS4 intervention in an adult population with MetS as well as genetically induced obese mice. <strong>Methods:</strong> An assay was optimized to …
-
The Modulating Effects of Dietary Fiber and Short-Chain Fatty Acids on Enterocyte Differentiation, Maturation and Turkey Coronavirus Infection
… is the availability of short-chain fatty acids (SCFA) in the intestinal lumen. These compounds are by-products of the bacterial fermentation of dietary fiber and serve as the primary energy source for enterocyte metabolism. The overall objective of this dissertation was to evaluate the effects of …
-
Effects of potato fiber and soluble corn fiber on the fecal microbiome of dogs with implications to inflammation
… butyrate, and total short-chain fatty acids (SCFA) without causing detriments to nutrient digestibility. We investigated this further by studying the prebiotic potential of PF by analyzing the fecal microbiome. We predicted that our previous results on fecal fermentation characteristics would …
-
Butyrate-Induced Expression of Proglucagon: Implications for Enteroendocrine Signaling and Intestinal Growth
… that fibers and short-chain fatty acids (SCFAs), particularly butyrate, are classes of nutrients capable of regulating the proglucagon gene. To examine this, we treated enteroendocrine L cells with butyrate and found increased proglucagon mRNA abundance. However, the mechanism by which …
-
Butyrate-induced expression of proglucagon: implications for enteroendocrine signaling and intestinal growth
… that fibers and short-chain fatty acids (SCFAs), particularly butyrate, are classes of nutrients capable of regulating the proglucagon gene. To examine this, we treated enteroendocrine L cells with butyrate and found increased proglucagon mRNA abundance. However, the mechanism by which …
-
Fermentation of resistant starch: implications for colonic health in the monogastric animal.
… by the microflora present, to produce gases and SCFA in varying amounts. These are utilised by the host animal as an energy source, with a low gut pH being maintained by the production of SCFA. The fermentation of carbohydrates within the colon is beneficial to the health of the gut, as the …
-
Signals and Sensory Mechanisms that Impact Campylobacter jejuni-Host Interactions
… -- organic acids and short chain fatty acids (SCFAs) -- in C. jejuni commensal colonization. C. jejuni has both acetate and lactate utilization pathways, as well as for acetate production. I observed that acetogenesis mutants incapable of producing acetate were deficient for colonization of the …
-
Fibre fermentation in the pig intestine : effect on metabolite production and nitrogen excretion
… pig intestines yields short-chain fatty acids (SCFA) and lactic acid, which have been found to improve gut health by favouring the growth of health-promoting bacteria such as Lactobacilli and Bifidobacteria, at the expense of pathogenic ones like Clostridium or Salmonella, which may enhance the …
Page 1 of 4