Global ETD Search
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Showing 1 to 2 of 2 for “"SCF ligase"”.
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Post-translational control of mitochondria by Fbxo7 in Parkinson's disease
… is as the substrate recruiting domain of an E3 SCF ubiquitin ligase complex. Mitochondrial defects have previously been detected in cells lacking Fbxo7 expression, although the precise mechanisms through which Fbxo7 protects cells from mitochondrial dysfunction and neuronal cell death are not …
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In vitro reconstitution of the ubiquitylation and disassembly of the eukaryotic replisome
… in the disassembly of CMG were known, viz the E3 ligase SCFDia2 and segregase Cdc48, very little was known about the mechanism of CMG disassembly. In the process of learning more about the disassembly of the replicative helicase from chromatin, I reconstituted the ubiquitylation of CMG and …