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Showing 1 to 2 of 2 for “"SCF E3 ubiquitin ligases"”.
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Functional Analysis of the F-box protein Fbxl17
… components of Skp1-cullin 1-F-box protein (SCF) E3 ligases. As essential components of the ubiquitin proteasome system (UPS) they are responsible for directing target proteins for ubiquitination. Fbxl17 is a relatively understudied member of the FBXL family of F-box proteins and, in breast …
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STRUCTURAL AND FUNCTIONAL STUDIES OF F-BOX-ONLY PROTEIN FBXO7 AND ITS INTERACTIONS WITH PROTEASOME INHIBITOR PI31
… role as the substrate-recognition subunit of the SCFFbxo7 (Skp1-Cul1-F-box protein) E3 ubiquitin ligase that catalyzes the ubiquitination of hepatoma up-regulated protein (HURP) and inhibitor of apoptosis protein (IAP). Fbxo7 also assumes various SCF-independent functions through interact with its …