Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"SCFβ-TRCP"”.
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Mechanisms of repression of the transcription factor NRF2 by KEAP1- and B-TrCP-dependent ubiquitin ligases and how the dysregulation of NRF2 contributes to lung cancer progression
… of the Neh6 domain of NRF2 is fundamental for SCFβ-TrCP-mediated degradation of the transcription factor. Previous work by other groups has indicated a potential role for a priming kinase to pre-phosphorylate the Neh6 domain and subsequently enhance GSK-3 mediated phosphorylation and resulting …
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Transcriptional and Post-Translational Mechanisms Contribute to Maintenance of Rest In Neural Tumors
… by modulation of E3 ligase or REST, SCF<sup>β-TRCP</sup>, and contribute to resistance of some cells to retinoic acid treatment.</p>