Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 160 for “"SCF"”.
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Characterization of SCF Ubiquitin-Ligase Subunits in Arabidopsis
… predicted to participate in the formation of the SCF-class of E3-ubiquitin ligase complexes. One such gene family encodes the Skp1-like class of polypeptide subunits, where 21 genes have been identified and are known to be expressed in Arabidopsis. The complexity of this family of Arabidopsis …
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A geometric method of fatigue SCF and fracture SIF assessment
… and stress concentration factors (SIF and SCF). The background and special theory was developed to give: 1. A better understanding of the singularities that commonly occur in sharp corners in ship connection details; 2. A quicker method for fatigue life estimation than present methods based …
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Developing Constrained p27 Peptides to Target the Oncogenic E3 Ubiquitin Ligase SCF-Skp2
… enzyme, and E3 - ubiquitin ligase. The SCF-Skp2 complex is one of 600 E3s in the human genome, and Skp2 serves as a substrate recognition subunit. Skp2 is an oncoprotein that exerts its oncogenic functions through degradation of specific substrates. A major target of SCF-Skp2 is the …
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Estudio de la ubicuitilación del complejo MRN mediada por SCF(bTrCP/FBXW7): implicaciones biológicas
… del sustrato. La ligasa de ubicuitina SCF está formada por una serie de subunidades entre las que se encuentran las proteínas F-box, cuyo papel es identificar a los sustratos específicos de esta ligasa. Dos de las proteínas F-box más destacadas de SCF son TrCP y FBXW7. Ambas son …
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SCF SKP2B - AND KPC1-DEPENDENT DEGRADATION OF CYCLIN-DEPENDENT KINASE INHIBITOR KRP1 AND CELL CYCLE REGULATION IN ARABIDOPSIS THALIANA
… depends on the 26S proteasome. Further, an SCF complex composed of CUL1 and SKP2b regulates KRP1 degradation. These results suggest that SCF SKP2B targets KRP1 for degradation by the 26S proteasome to regulate the G1-S transition of the cell cycle. In addition to SCF SKP2B-mediated KRP1 …
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Credibility and scale as barriers to uptake and use of seasonal climate forecasts in Bobirwa Sub-District, Botswana
Seasonal climate forecasts (SCF) can play a crucial role in reducing vulnerability to climate variability, particularly for rural populations reliant on agriculture for their livelihood. The use of disseminated SCF by farmers in decision-making could reduce losses and maximise benefits in …
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Supply Chain Finance: Exploring the State of Adoption with Small Business Suppliers in U.S. Defense Procurement Contracts
<p>Innovative supply chain finance (SCF) practices offer alternative approaches to relief of cash flow distress for suppliers in an extended enterprise by enhancing access to and affordability of working capital. Adopting optional SCF instruments can be especially beneficial for small–medium-sized …
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SME Globalisation and Supply Chain Finance: Factors to Adoption of Technology-based Solutions
… the development of robust Supply Chain Finance (SCF) solutions to enhance financial resilience and operational efficiency. Despite the growing necessity of technology-based SCF solutions, such as blockchain and Bank Payment Obligation (BPO), SMEs face substantial barriers to adoption due to …
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Select novel carbohydrates affect glycemic and insulinemic response, energy value, and indices of gut health as measured using canine, avian, rodent, and in vitro model systems
… fiber dextrins (SFD), and soluble corn fibers (SCF) - for properties that could positively impact health outcomes. Study 1 measured in vitro hydrolytic digestion characteristics, glycemic and insulinemic responses, and true metabolizable energy (TMEn) content of select SFDs and Pulls. Soluble …
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Automatic syntactic analysis of learner English
… constructs such as subcategorization frames (SCFs). SCFs have attracted much research attention as they provide unique insight into the interplay between lexical and structural information. An automatic SCF identification system adapted for learner language is needed to facilitate research on …
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Disentangle model differences and fluctuation effects in DPD simulations of diblock copolymers
… obtained from self-consistent field (SCF) calculations. Since SCF theory is a mean-field theory neglecting system fluctuations/correlations while DPD simulations fully incorporate such effects, the model differences are mixed with the fluctuation/correlation effects in their …
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The Immunohistological Features of Acquired Bilateral Nevus of Ota-like Macules: Comparison with Melasma and Nevus of Ota
… findings of NKI/beteb, stem cell factor (SCF), c-kit, factor VIIIa-related antigen and vascular endothelial growth factor (VEGF) were examined and quantified by image analysis. RESULTS: In ABNOM, the amount of lesional dermal pigmentation and melanocytes were increased compared to …
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Responding to children affected by armed conflict: A case study of Save the Children Fund (1919-1999).
Save the Children Fund (SCF) was at its foundation in 1919 a value-driven organization. The values, or guiding principles, of the founding generation are the lens through which I look at the history of SCF, and the associated histories of war and peace, human rights and NGO-state relations. These …
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Stress reduction in a plate with a hole by applied induced strains
… could reduce the stress concentration factor (SCF) from 3 to 2. With non-axisymmetric applied induced strain distribution the SCF could be reduced to 1.45. Numerical optimizations based on finite element simulations were also carried out for a composite plate with a hole and similar reductions …
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Soluble C-Kit Receptor Level May Be a Serological Marker for Predicting the Extent of Upper and Lower Airway Inflammation
… activation and this stem cell factor (SCF)/c-kit pathway leads to eosinophil infiltration. We investigated whether SCF/c-kit pathway induced inflammation is associated with both upper and lower airway inflammation. METHODS: We enrolled 71 allergic asthma patients with rhinitis (group I) …
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Variational Monte Carlo estimation of the dissociation energy of CuH using correlated sampling
… value; the method is comparable with SCF and simple pseudopotential calculations. The dipole moment differs from the best theoretical estimate by about 50% what is again comparable with other methods (Complete Active Space SCF and pseudopotential methods).
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A comprehensive ab initio study of gallium and arsenic containing molecules
… are carried out at the self consistent field (SCF) Hartree-Fock level of theory, using analytic energy gradients for rapid geometry optimization. In addition, the SCF results are compared with theoretical predictions obtained at the coupled cluster level of theory including all single and …
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Discovery and Effects of Pharmacological Inhibition of The E3 Ligase Skp2 By Small Molecule Protein-Protein Interaction Disruptors
… protein 2), one component of the SCF E3 ubiquitin ligase complex, directly interacts with Skp1 and indirectly associates with Cullin1 and Rbx1 to bridge the E2 conjugating enzyme with its protein substrate to execute its E3 ligase activity. Skp2 is an Fbox protein (due to it …
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Identification of Epo-independent red cell progenitors : the E-cad+ progenitors
… Den Wachstumsfaktoren stem cell factor (SCF) und Erythropoietin (Epo) fällt dabei eine entscheidende Rolle zu. Unter ihrem synergistischen Einfluß lassen sich Epo-abhängige Zellpopulationen, die sich aus BFU-E und CFU-E Typ Zellen zusammensetzen, ausreichend amplifizieren (Panzenböck et …
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The role of fibrolast-derived cytokines on melasma
… growth factor (HGF), stem cell factor (SCF), tumor necrosis factor(TNF)-α, interleukin(IL)-1α, and c-kit. The results of staining were analyzed by estimation of three dermatologists and computerized image analysis. There were marked epidermal thinning of the lesional sites than those of …
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