Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"SCD1"”.
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The Role of the SCD1 Protein in Targeting PIN2 Protein in Arabidopsis Thaliana
… proteins in the plasma membrane. The <italic>SCD1<italic> (stomata cytokinesis defective) gene encodes a protein containing a DENN domain, which is predicted to function as a RAB-GEF, which may be important in membrane protein targeting. The <italic>scd1-1<italic> allele is a temperature …
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Examination of auxin transport and root development in the scd1-1 mutant in Arabidopsis thaliana
… and endosomal cycling of these proteins. The SCD1 (stomatal cytokinesis defective) protein has a domain structure that suggests it may function in Rab dependent protein trafficking. We examined IAA transport, IAA efflux protein localization, and dependent physiological processes in the …
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The identification and characterization of two murine genes regulated by the level of dietary fat
… fat on hepatic stearoyl CoA desaturase 1 (Scd1) and Low Fat Mammary 1 (Lfm1) expression and describe the structural organization of the Lfm1 gene. Scd1 and Lfm1 were isolated from a cDNA library constructed from mammary gland tissue of BALB/c mice fed a low fat diet (Elliott et al. 1993. …
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Identification of Tissue Distribution and Regulation of Bovine Stearoyl-Coa Desaturase by Hormones and Nutrients
… desaturase-1 (SCD) and the regulation of SCD1 protein expression by dietary fat, insulin, polyunsaturated fatty acids (PUFA), and linoleic acid (cis-9, cis-12 18:2). The first study examined tissue distribution of SCD1 protein in Holstein calves (n=6/diet) fed one of four milk replacer …
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Spatial Control of CDC42 Activation Regulates Cell Width and Growth Zone Formation
… Cdc42 guanine-nucleotide exchange factor (GEF) Scd1 and the second by the GTPase activating protein (GAP) Rga4. Deletions of rga4 and scd1 had additive effects on cell width, and the proteins localized independently of one another, with Rga4 located at the cell sides and Scd1 at the cell tips. …
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Associations between gene variations and milk composition in New Zealand dairy cattle: A thesis submitted in fulfilment of the requirements for the Degree of Doctor of Philosophy at Lincoln University
… stearoyl-CoA desaturase (Δ-9-desaturase) gene (SCD1), the perilipin-2 gene (PLIN2) and the lipin-1 gene (LPIN1). These genes were chosen because they had either been implicated in fatty acid (FA) metabolism in mammary gland cells, or potentially regulated milk fat synthesis. They were screened …
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Effect of pregnancy on adipose tissue biology in a mouse model of obesity
… involved in de novo lipogenesis (ME1, FANS and SCD1 Dgat2), consistent with a direct role for ERα activation in curtailment of fat expansion. Although the primary human study lacked sufficient power to adequately address the hypothesis, PPT significantly suppressed SCD1 mRNA levels in visceral …
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Fatty acid metabolism and SNPs related to obesity in a longitudinal study of Swedish men: Predictors of metabolic syndrome
… single nucleotide polymorphisms (SNPs), on the SCD1 (stearoyl-CoA desaturase) gene and SNPs that had previously been associated with body mass index (BMI) or obesity in genome-wide association studies, with variables reflecting metabolic health. The variables reflecting metabolic health were …
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Mechanisms into the development of fatty liver disease: role of free fatty acids and alcohol
… increased expression of stearoyl-CoA desaturase (SCD1) and decreased peroxisome proliferator activated receptor alpha (PPARα) expression at 15:1 and 25:1 (P<0.05), while all ratios showed a significant decrease in the cannabinoid receptor (CB2) expression compared to control but actually increased …