Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"SCA5"”.
-
Molecular and genetic characterization of spinocerebellar ataxia type 5 (SCA5)
Spinocerebellar ataxia type 5 (SCA5) is a progressive neurodegenerative disorder, which primarily affects the cerebellum. The disease is inherited in an autosomal dominant pattern, with onset typically occurring in the 3rd or 4th decade of life. In 1994, SCA5 was mapped to the centromeric region of …
-
Elucidating the reversibility of ataxia
… are implicated in spinocerebellar ataxia type 5 (SCA5) and spectrin-associated autosomal recessive cerebellar ataxia type 1 (SPARCA1), respectively. Our mouse model, lacking b-III spectrin (KO), mimics the progressive human phenotype displaying motor deficiencies as well as reduced Purkinje cell …