Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 58 for “"SARS-CoV-2 infection"”.
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NEW-ONSET HYPERGLYCEMIA AFTER SARS-COV-2 INFECTION
… were hospitalized for coronavirus disease 2019 (COVID-19) have a higher prevalence of hyperglycemia. By altering glucose homeostasis, cytokine release brought on by The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection may hasten the onset of metabolic changes. Here, they are …
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Developing novel prophylactic approaches against SARS-CoV-2 infection
Prevention of SARS-CoV-2 entry into cells through the modulation of viral host receptors, such as ACE2, could represent a new chemoprophylactic and therapeutic approach for COVID- 19 complementing vaccination. However, the mechanisms controlling ACE2 expression remain elusive, partly due to low …
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Profiling Host Respiratory Responses to SARS-CoV-2 Infection
… Over the past three years, we have studied SARS-CoV-2 infection through the lens of single-cell genomics, querying pre-existing single-cell datasets, developing in vitro models of disease, validating animal models of infection, and profiling human samples with our clinical collaborators, all …
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Neutralising antibody responses in acute hepatitis C and SARS-CoV-2 infection
… cells. Understanding the nAb response in early infection informs preventative and therapeutic interventions. The acute phase of hepatitis C virus (HCV) infection is characterised by two bottlenecks of viral diversity, one at the initiation of infection (selection of transmitted/founder (T/F) …
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Investigating the neurological effects of SARS-CoV-2 infection on the brain
SARS-CoV-2 and its associated disease COVID-19 is still a major public safety concern, three years into the global pandemic. While effective vaccines are readily available to protect against infection, major questions surround the long-term effect of SARS-CoV-2. Several patients report suffering …
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Characterization of pro- and anti-inflammatory immune responses in SARS-CoV-2 infection
Viral infection stimulates the immune response to produce many cytokines and chemokines, the proteins imperative to fight a brewing infection. This response begins through recognition of pathogen-associated molecular patterns (PAMPs) from the virus, or from other signatures characteristic of tissue …
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Determinants of functional capacity and work ability post SARS-COV-2 infection in miners
… Insufficient data exists on the sequelae of COVID-19 and its impact on function and work ability among workers. The aim of this study was to investigate the determinants of functional capacity and work ability in miners following COVID-19 disease. Methods: This cross-sectional study recruited …
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Digital immunoassay for rapid detection of SARS-CoV-2 infection in a broad spectrum of animals
The student, Siyan Li, accepted the attached license on 2024-12-11 at 14:36.
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A comparison of maternal and neonatal outcomes of pregnant women with and without evidence of SARS-CoV-2 infection in the Western Cape, South Africa
Background: SARS-CoV-2 infection in pregnancy has been associated with poor pregnancy and neonatal outcomes. While SARS-CoV-2 infection itself could partly account for high maternal mortality rates observed in the Western Cape, indirect effects of the pandemic such as movement restrictions and …
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DISSECTING THE MOLECULAR MECHANISMS RELATED TO THE ONSET OF NEUROLOGICAL COMPLICATIONS IN THREE CELLULAR MODELS OF SARS-COV 2 INFECTION: IPSC-DERIVED MOTO R NEURONS, IPSC-DERIVED DOPAMINERGIC NEURONS, IPSC DERIVED-HUMAN CORTICAL ORGANOIDS.
Although COVID‐19 typically leads to respiratory disorders, recent evidence show that acute and sub-acute neurological complications are reported in patients not only with severe disease, but also in otherwise minimally symptomatic or asymptomatic people [1–3]. Notably, up to 65% of COVID-19 …
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Naujai diagnozuotas cukrinis diabetas po COVID-19 infekcijos /
Four years since the beginning of the COVID-19 pandemic, scientists are still observing the long-term consequences of the disease. Some symptoms (fatigue, shortness of breath, headaches) persist in the human body for weeks, months, or even years after the illness, and a separate term has been …
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Mechanisms of virus infection of human airway epithelium cultured at an air-liquid interface (HAE-ALI)
… HAE-ALI is also a useful tool for studying infection of respiratory viruses, such as SARS-CoV-2 and influenza virus. Understanding SARS-CoV-2 infection of HAE-ALI and the caused epithelial damage has significance and implications in developing effective antivirals. we found that SARS-CoV-2 …
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IMPACT OF SARS-COV-2 RESPIRATORY INFECTION ON CLINICAL OUTCOMES AND NEED FOR NON-INVASIVE VENTILATORY SUPPORT IN ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A SINGLE-CENTER, PROSPECTIVE, OBSERVATIONAL STUDY
Viral and bacterial infections are the main cause of COPD exacerbations, accounting for 25% and 26% of cases respectively. To date no conclusive data are available on the risk of COPD exacerbations triggered by SARS-CoV-2. The present study was primarily aimed to identify the risk of acute …
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Severe Acute Respiratory Syndrome Coronavirus-2 Vaccine Development: A Virus-Like Particle Vaccine Approach
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 as a highly infectious virus that spread rapidly and was declared a pandemic by the World Health Organization (WHO) in March of 2020.1 SARS-CoV-2 infection causes respiratory disease (Coronavirus Disease; COVID-19), …
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The reactivation of Kaposi's Sarcoma-associated Herpesvirus (KSHV) by SARS-CoV-2 in non-hospitalised HIV-infected patients
… severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic, occurred primarily in densely populated, low-income communities which are additionally burdened by a high prevalence of Human Immunodeficiency Virus (HIV) and Kaposi's Sarcoma Associated …
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Avaliação de genes auto inflamatórios em crianças com Síndrome Inflamatória Multissistêmica Pediátrica (SIM-P) associada à infecção pelo SARS-CoV-2
… is an inflammatory condition associated with SARS-CoV-2 infection. It is characterized by fever, prominent gastrointestinal symptoms, mucocutaneous manifestations, respiratory symptoms, and shock. The occurrence of P-MIS may be linked to innate immunological errors that selectively affect the …
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Investigating the Role of Viral Long Non-Coding RNAs During Human Cytomegalovirus Latency
… is a ubiquitous human herpesvirus. Primary infection with HCMV in healthy individuals is generally asymptomatic but the virus is never cleared and can go on to establish lifelong latency in cells of the early myeloid lineage. During latency, the virus reduces its gene expression programme …
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HOST RESPONSE TO PRIMARY AND SECONDARY CORONAVIRUS EXPOSURES AND POTENTIAL GERMINAL CENTER MECHANISMS ASSOCIATED WITH PROTECTION DURING RE-EXPOSURE
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019, causing coronavirus disease 2019 (COVID-19), a disease of varying symptoms and degrees of severity. As the virus spread globally, it was clear that certain demographics of people were more likely to experience severe …
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