Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"SARS-COV2"”.
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CELLULAR AND MOLECULAR PATHWAYS CONTROLLING SARS-COV2 ASSEMBLY AND EGRESS
SARS-CoV-2 is an enveloped, single-stranded, positive-sense RNA virus belonging to the family of Coronaviridae. Coronaviruses assemble on intracellular membranes, differently from many other RNA viruses that assemble and egress directly at the plasma membrane. This feature adds an additional layer …
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Impact of SARS-COV2 pandemic on emergency surgical services at Groote Schuur Hospital
… severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic on emergency surgery services revealed an 87.8% decrease in procedures. The aim of the study was to determine the impact of the coronavirus 19 (COVID-19) pandemic on the number of emergency surgical operations performed at …
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SARS-CoV2 y embarazo. Análisis de variables obstetricias y parto durante la pandemia en España
La infección por el coronavirus SARS-CoV-2 ha generado una de las mayores emergencias sanitarias a nivel mundial y sigue estando activa. Las infecciones producidas por otros virus respiratorios se han asociado a complicaciones en el embarazo y parto, por lo que la pandemia por COVID-19 puede …
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Marcadores inflamatorios y factores clínicos asociados en niños y adolescentes con infección por SARS COV-2 y la relación con su severidad en dos instituciones de Bogotá
… en población pediátrica con infección por SARS CoV-2, y su relación con la severidad de la enfermedad, por lo que se pretende realizar un estudio de casos y controles en niños y adolescentes del Hospital Universitario Clínica San Rafael (HUCSR) y de la Clínica Infantil Colsubsidio (CIC) …
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Differential analysis of scRNA-Seq data to characterize epithelial cells in health and disease
… such as allergic inflammation or infection with SARS-CoV2. Studies of these tissues and the cells of which they are composed can allow us to better understand how epithelia respond to diverse perturbations, leading to broad insights in how to mitigate dysfunction and promote health. The recent …
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Development and Characterization of a Modified Vaccinia Ankara Vaccine Candidate Expressing the SARS-CoV-2 Spike Glycoprotein
… severe acute respiratory syndrome coronavirus 2, SARS-CoV-2. Given the ongoing COVID-19 pandemic and the continued evolution of the virus to escape host immunity, new vaccines and refinement of first-generation vaccines to improve protection against SARS-CoV-2 variants of concern is vital. In …
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Quantifying the Effect of Disease Characteristics on the Outcomes of Interventions Using Mathematical Modelling
… for the transmission dynamics of influenza and SARS-CoV2, examining the impact of their characteristics on intervention outcomes. Simulations and sensitivity analysis show that the length and infectiousness profile during various stages of illness significantly affect intervention outcomes. The …
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Áhrif COVID-19 á líðan og störf kennara í grunnskólum Reykjanesbæjar
… á heimsvísu með tilkomu COVID-19 sem SARS-CoV2 veldur voru skorður settar á skólastarf íslenskra barna vegna fjölda- og fjarlægðartakmarkana. Stjórnendur urðu að bregðast hratt og örugglega við breyttum raunveruleika og aðlaga skólastarfið að þeim nemendafjölda og því rými sem hver og …
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Caso de estudio: Impacto de la pandemia originada por el COVID-19 en la exportación de cacao en el año 2020
… the influence of the pandemic generated by the Sars-Cov2 virus, commonly called Covid-19 or coronavirus in cocoa exports for the period most critical of the pandemic that was in 2020, both for Peru and for Ecuador, which is a direct competitor of Peruvian cocoa. In order to determine if the …
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Characterization of viral- and fungal-reactive CD4+ T cells in healthy and diseased
… CD4+ T cell responses in the contexts of SARS-CoV2 vaccination and chronic intestinal inflammation, with focus on the roles of pre-existing T cell repertoires, antigen specificity and cross reactivity. The first study demonstrates that the quality of immune responses to …
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Inducible Epithelial Resistance Against Acute Viral Pneumonia and Chronic Asthma
… programs. The influenza pandemic of 1918 and SARS-CoV2 pandemic of 2019-2020 are cautionary reminders demanding the need for novel treatment strategies. Moreover, in addition to causing acute disease, respiratory virus infections are often complicated by chronic lung pathologies, such as …
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Inducible Epithelial Resistance Against Acute Viral Pneumonia and Chronic Asthma
… programs. The influenza pandemic of 1918 and SARS-CoV2 pandemic of 2019-2020 are cautionary reminders demanding the need for novel treatment strategies. Moreover, in addition to causing acute disease, respiratory virus infections are often complicated by chronic lung pathologies, such as …
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Development of Original and Notable Techniques for Protein Analysis, Native Identification, and Characterisation
… the overall conclusion is based on a study of SARS-COV2 seroprevalence in the swiss canton of Zürich between December 2019 and January 2021. This study was conducted on two cohorts, the University Hospital patients, and the blood donation services of Zürich.
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Impacto de los modelos híbridos en la felicidad de los trabajadores como consecuencia del Covid-19
… sin precedentes cercanos, la aparición del Sars-Cov2, un virus altamente contagioso y sin cura, que cambió la cotidianidad de la población, provocando la declaración de una pandemia mundial que afectó directamente la interacción de las personas con su entorno.
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Análise da situação epidemiológica da dengue no Estado do Rio Grande do Norte, Brasil, no período de 2016 a 2020
… on coping with the current Coronavirus pandemic (SARS-COV2).
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Antibody technology identifies distinct mechanisms controlling the lengths of filopodia-like structures
… an *in vitro* system for filopodia triggered by SARS-CoV2 nucleocapsid protein, with limited success, but promising results for further study. This work shows that novel actin regulatory mechanisms can be identified based on antibody reactivity in the FLS system and gives new candidate molecules …
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B cell memory in STAT3 Hyper-IgE Syndrome: Cytokine integration, IgE regulation, and the architecture of human memory B cell subsets
… B cell and IgG responses induced by SARS-CoV-2 vaccination (Aim 3, Chapter 5). The SARS-CoV-2 specific B cell response in STAT3 HIES was quantitatively similar but phenotypically skewed compared to HD. Furthermore, the SARS-CoV2 IgG response in STAT3 HIES was significantly delayed and …
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Antibody-Effector Functions in Antiviral Response
… tools in the settings of dengue virus and SARS-CoV2 infection, as novel therapeutics for the selective disruption of Fc-FcγR interactions, and as research tools for interrogating the B cell receptor (BCR) glycan structure.</p>
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Investigations Of The Effects Of Selected Y-chromosome Encoded Gene Deletion And Viral Infection On Testicular Function In A Mouse Model
… biopsies obtained from men who succumbed to SARS-CoV2 (COVID-19) infection, many with underlying conditions, revealed extensive testicular damage in the absence of active viral infection of the testes, despite the presence of the viral cellular receptor, angiotensin converting enzyme 2 …
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Investigating clonal hematopoiesis in rhesus macaque and human
… We next subjected our CH RM model to SARS-CoV2 infection given the overlapping role of inflammation in COVID-19 disease pathophysiology. However, we did not find evidence supporting CH worsening COVID-19 disease pathophysiology. This was confirmed by screening CH mutation in COVID-19 …
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