Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"SAP motif"”.
-
Cytokine modulations by type I interferon suppression-negative and NF-κB activation-negative Porcine Reproductive and Respiratory Syndrome Virus
… IFN antagonist, and leucine at position 135 in SAP (SAF-A/B, Acinus, and PIAS) motif is determined as the active residue for IFN suppression. For NF-κB activation, the viral nucleocapsid (N) protein has been found as the effector protein, and the nuclear localization signal (NLS) in N overlaps …
-
Innate immune modulation and pathogenic basis for porcine reproductive and respiratory syndrome virus
… antiviral protein translation. The functional motif for both IFN suppression and host mRNA nuclear retention were identified in nsp1β, and mutations in the motif results in the IFN-suppression-negative and host-mRNA nuclear retention-negative. To examine the pathogenic consequence of these …