Global ETD Search
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Showing 1 to 4 of 4 for “"SAHH"”.
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Investigation of a Possible Multi-enzyme Complex Involved in Nicotine Biosynthesis in Roots of Tobacco (Nicotiana tabacum)
… encoding S-adenosylhomocysteine hydrolase (SAHH) in N. sylvestris and a gene encoding SAHH in N. tabacum were cloned instead. SAHH is an enzyme of the S-adenosylmethionine (SAM) recycling pathway, which also includes SAM synthetase (SAMS) and methionine synthase (MS). These results led to …
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Investigation of Protein-Protein Interactions among Nicotine Biosynthetic Enzymes and Characterization of a Nicotine Transporter
… enzyme S-adenosylhomocysteine hydrolase (SAHH) has been proposed. To further explore this hypothesis, protein-protein interactions among nicotine biosynthetic enzymes PMT, MPO and SAHH were investigated using yeast two-hybrid assays and co-immunoprecipitation experiments. The yeast …
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THE METHIONINE CYCLE AS A NOVEL THERAPEUTIC TARGET IN NPM1C DRIVEN ACUTE MYELOID LEUKEMIA
… known to activate adenosylhomocysteinase (SAHH) and reduce SAH levels, and showed that it synergizes with SAM, inhibits growth and promotes monocytic differentiation of NPM1c-AML growth in vitro. In summary, in this PhD project, we demonstrate that the SAM/SAH unbalance is at the basis of …
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Physiological and molecular mechanisms associated with performance, immunometabolic status, and liver function in transition dairy cows fed rumen protected methionine or choline
… P = 0.01) S-adenosylhomocysteine hydrolase (SAHH) and CBS (1.16 vs. 1.02; SEM = 0.07; P = 0.04) as well as lower (23.4 vs. 29.7 nmol product h-1 mg protein-1; SEM = 2.9; P = 0.04) MTR activity were also detected in MET but not CHOL-supplemented cows. Although greater (1.07 vs. 0.93; SEM = …