Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"SAHF"”.
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Nucleolar dynamics in cellular senescence
… of senescence-associated heterochromatin foci (SAHF) formation were identified along with enlarged nucleoli in OIS. Notably, SAHF-positive cells exhibited significantly enlarged nucleoli over SAHF-negative cells, suggesting alterations in nucleolar area may link with SAHF formation. Conversely, …
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Autonomous and non-autonomous regulation of chromatin structure during cellular senescence
… senescence-associated heterochromatic foci (SAHF). We find that NOTCH1 inhibits SAHF formation at least partially through transcriptional repression of a critical structural component, high-mobility group A (HMGA). Using ATAC-sequencing (assay for transposase accessible chromatin) we …
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Stay-at-home Fathers in Contemporary Urban China
This research investigates stay-at-home fathers (SAHFs) as an emerging gendered identity in contemporary urban China. Being a SAHF constitutes an unconventional gender role in China, which has been marginalised by longstanding prejudice against men who are not the main wage-earners in the family …
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The role of High Mobility Group A1 protein in transcriptional regulation of cellular senescence
… of senescence-associated heterochromatic foci (SAHF). Moreover, senescent cells secrete a series of functional molecules, which are collectively called senescence-associated secretory phenotype (SASP). These molecules can be beneficial or detrimental depending on the biological context. High …
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Regulatory Landscapes Associated With Changes In Nuclear Architecture
… of Senescence Associated Heterochromatic Foci (SAHF), an important phenotypic feature of RIS, consisting of striking re-organisation of heterochromatic regions. In terms of network connectivity, RIS interactions were characterised by increased separation between any two genomic regions. The …
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Masculinity, fathers and family literacy: Glimpses behind the ‘hard-man’ front
… involuntarily, for that of stay-at-home father (SAHF). Photovoice and a feminist, Freirean research methodology innovatively supported the collective exchange of the men’s compelling narratives of care. A series of community-based photography workshops, group discussions and follow-on one-to-one …