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Showing 1 to 20 of 54 for “"S100"”.
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DAMPening synovial activation in osteoarthritis: taking the S100-road
Contains fulltext : 132082.pdf (Publisher’s version ) (Open Access)
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Comparative Biochemistry of Drug-Binding Proteins in Calmodulin/S100 Family
<p>Calmodulin is a member of a class of structurally and functionally related proteins. Calmodulin is widely distributed among eukaryotes, and the amino acid sequence of calmodulin is highly conserved. The protein contains multiple structural domains and has multiple activities in vitro, including …
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A molecular investigation of the antimicrobial functions of the human S100 host-defense proteins
… functions of four host-defense proteins of the S100 family of proteins: calprotectin (CP), S100A12, S100A7, and S100A15. In the first half of this thesis, we elucidate the Zn(lI)-binding and antimicrobial properties of S100A12 and S100A7 through the use of solution and microbiology studies. We …
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SUBCONCUSSIVE HEAD IMPACT EFFECT ON PLASMA EXPRESSION OF S100-BETA AND PINCH PROTEINS IN COLLEGIATE FOOTBALL PLAYERS
… of repetitive subconcussive impacts on plasma S100β and PINCH levels and concussion-related symptom score were examined. The first aim was to investigate the acute repetitive subconcussive impact effect by comparing the biomarker levels at pre and post full-gear practice, followed by examining …
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Flower Isoforms Increase Expression in Response to Cellular Stress and Modulate S100 Expression in Cutaneous Squamous Cell Carcinoma Cells
… that transcript and protein expression of S100A7, S100A8, and S100A9 were decreased in hFWE3 and hFWE4 over-expressing cells. Transcripts for these S100 isoforms were strikingly increased in human cSCC compared to normal skin. Exposure of cSCC cells to stress stimuli including ultraviolet …
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18F-markierte S100-Proteine als potentielle Radioliganden für die funktionelle Charakterisierung des Rezeptors für advanced glycation endproducts (RAGE) in vitro und in vivo
Die Interaktion von S100-Proteinen mit dem Rezeptor für advanced glycation endproducts (RAGE) wird als hoch relevant bei der Entstehung, Manifestation und Progression verschiedener entzündlicher Erkrankungen sowie bei der Tumorigenese gewertet. Das tiefergehende Verständnis der Interaktion von …
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Tumor infiltrierende dendritische Zellen im Adenokarzinom des Uterus : eine Studie von 115 Neoplasien mit Korrelation zu anderen Prognosefaktoren und zur Überlebensrate
… untersuchten, ob die Tumor-Infiltration durch S100 positive dendritische Zellen ein prognostischer Marker für das Endometriumkarzinom sein könnte. In dieser retrospektiven Studie wurden 115 Gewebeproben von Endometriumkarzinomen mit bekanntem histologischem Grading, Hormonrezeptorstatus, Ki-67, …
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Resistance Factor for Cold-Formed Steel Compression Members
… predicted strengths are calculated with the AISI-S100-07 Main Specification and the AISI Direct Strength Method. The test-to-predicted strength statistics are employed with the first order second moment reliability approach in AISI-S100-07 Chapter F as well as a higher order method to calculate …
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The effect of synthetic cannabinoids on wound healing of chondrocytes monolayers and pseudo 3D cartilage tissue. Effect of different concentrations of synthetic cannabinoids WIN55, 212-2, URB602 and HU-308 with and without their antagonists on wound healing of chondrocyte monolayers and pseudo 3D cartilage tissue.
… type-I, collagen type-II, fibronectin and S100 proteins were detected using immunofluorescence and verified quantitatively using ELISA based techniques, following treatment with 1μM and 2μM of WIN-2, for both 2D monolayers and 3D sheets. Treating chondrocytes with 1μM of WIN-2 significantly …
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Vías transdérmicas de administración de fármacos
… y de barrido) y de inmunohistoquímica (proteína S100, vimentina, colágeno IV). Se valoraron, además, los cambios inducidos por las técnicas de aplicación y las moléculas en el espesor relativo de dermis/epidermis, de densidad de la red capilar papilar dérmica.
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Development and Evaluation of Ternary Amorphous Solid Dispersion of Poorly Water-soluble Compounds
… three different polymers (i.e., EPO, HPMCAS, and S100), the miscibility study indicated the best miscibility of CUR and RES with EPO. From the crystallization kinetics study, we inferred that EPO has a better crystallization inhibition effect than HPMCAS and S100. Finally, interaction studies …
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Nanomanipulator perturbation of dust crystals in a GEC rf plasma cell.
… system for controlled dust manipulation, the S100 nanomanipulator, is examined. Two experiments were conducted with this probe to characterize the response of both the plasma and a dust crystal. First, the dust was exposed to the probe to determine the length scale of interaction between the …
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Single-Cell Lineage Tracing Of Cancer Metastasis
… we observe evidence for in vivo propagation of S100 family gene expression across clonally distinct metastatic subpopulations.
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Molecular mechanisms in obesity-associated metabolic disease
… low calorie diet treatment. Using this approach, S100 calcium binding protein A1 (S100A1), Zn-alpha2-glycoprotein (ZAG), and CCAAT/enhancer binding protein alpha (C/EBPα) were identified as potential susceptibility genes. Subsequent genetic association study revealed a link between S100A1 and …
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Glucose-Induced Apoptosis of Schwann Cells In vitro
… levels for one to seven days. The glial marker S100 monoclonal antibody identified Schwann cells, and apoptosis was detected using the terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) method. Approximately 50% of the Schwann cells exposed to elevated glucose levels …
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Role of CD47 In Red Cell Apoptosis (Eryptosis)
… and C-terminal antibodies against CD47. S100 proteins were found to be up-regulated in CD47 IPs and five lipid raft components were found up-regulated in CD47 IPs when compared against normal erythrocyte membranes (’ghosts’). This study concludes that the CD47 eryptosis pathway involves …
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Differentiation plasticity of stromal vascular fraction cells towards adipose tissue and endothelial structures
… here show that the SVF contains a CD31-, S100+ cell type which can differentiate into adipocytes and EC. The SVF also comprises CD31+ cells that, although they have an endothelial phenotype, can be converted into mature adipocytes. These findings demonstrate the potency of SVF cells to …
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Study of controlled release of dapsone from modified montmorillonite and polymer matrices
… combination with an anionic copolymer (Eudragit S100). The effects of the excipients on the API dissolution rate were studied from their release profile in simulated intestinal fluid (pH=7.4) at 37+/-0.5 C. In the first part of the research, ionizable Dapsone was intercalated in the interlayers …
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Structural and thermal performance of cold-formed steel studs with slits
… ratios is proposed and verified within the AISI S100 reliability framework. Subsequently, a parametric three-dimensional heat-transfer study quantified the dependence of heat flux on geometry and slit parameters, providing a quantitative basis for thermal performance gains and their balance with …
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