Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 114 for “"S. Typhimurium"”.
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Extracytoplasmic stress response systems in S. Typhimurium
… thesis was to characterise the ESR systems of S. Typhimurium to widen our current knowledge of genes involved in these systems and their role in the pathogenesis of S. Typhimurium with the ultimate aim of identifying possible candidate vaccine genes that may be used in future therapeutics against …
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The Role of CheV in S. typhimurium Chemotaxis
… systems of Escherichia coli and Salmonella typhimurium are thought to be virtually identical. However, recently a putative chemotaxis gene, cheV, was found to be present in S. typhimurium but not in E. coli. Sequence analysis shows that the CheV protein shares sequence similarity to both …
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Genetic analysis of RNA polymerase/transcriptional activator interactions at thepepT promoter of S. typhimurium
… anaerobic induction of the pepT gene of S. typhimurium. Each of these mutations (G311E, G311R, L289F, R317H, W320ter) affects an amino acid in the C-terminal region of the alpha subunit. Phenotypic characterization shows that four of the five mutations have relatively specific effects on …
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Interactions between salmonella typhimurium and human gut bacteria
Salmonella enterica subsp. enterica serovar Typhimurium is an important enteropathogen that causes human morbidity and mortality worldwide. It is essential to study the interaction between Salmonella and the gut bacteria to elucidate the elements that influence the ability of the pathogen to …
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Antimicrobial effect of lime juice and java plum juice on foodborne pathogenic bacteria
Escherichia coli O157:H7, Salmonella Typhimurium, Staphylococcus aureus, and Listeria monocytogenes are common foodborne pathogens in the United States. With the advent of more consumers seeking chemical-free treatments to control pathogenic organisms in food, there has been an increasing interest …
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Development of Immunomagnetic Capture (IMC) Based Techniques For the Detection of Salmonella in Poultry Carcass Rinse Fluid
… could detect at least 102 cfu/ml of S. Typhimurium in broiler carcass rinse fluid (CRF) samples. IMC-ELISA, IMC-PCR, and IMC-Taqman® PCR were initially tested using 0 to 106 cfu/ml of pure culture S. Typhimurium. Each detection method was tested using artificially contaminated CRF …
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Association of <i>glpQ</i> with serum-resistance in <i>salmonella typhimurium</i>
<p><em>Salmonella typhimurium</em> is a leading cause of infectious human gastroenteritis and systemic disease when it escapes into the bloodstream. The human serum complement system is central in fighting systemic bacterial infections. <em>S. typhimurium</em> exhibits resistance to killing by …
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Genomic diversity and genomic typing of Salmonella enterica serovar Typhimurium
Salmonella enterica serovar Typhimurium (S. Typhimurium) is one of the most frequently reported serovars in Australia. In the first study of this thesis, 21 S. Typhimurium genomes from Salmonella reference collection A (SARA) were sequenced. Together with 47 publicly available S. Typhimurium …
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Investigating the effect of mutations in lipopolysaccharides (LPS) (O-antigen and Core region) of Salmonella Typhimurium on the colonisation of “microgreens”
… have significantly increased. Salmonella Typhimurium, a common foodborne pathogen, has been implicated in several outbreaks, underscoring the importance of understanding its interactions with fresh produce. This study aimed to investigate the effect of mutations in lipopolysaccharides …
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Genome-scale metabolic modelling of Salmonella and Lactobacillus species
Salmonella Typhimurium is a major cause of morbidity and mortality in humans. It is also a commonly used model organism for intracellular Gram negative pathogens, a group of bacteria that is becoming increasingly resistant to available antibiotics. Systemic Salmonella infection involves …
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An integrated approach to ciprofloxacin susceptibility analysis and high-throughput bacterial phenotyping in Salmonella
… globally, and the ST313 lineage of Salmonella Typhimurium are responsible for much of the burden of salmonellosis in sub-Saharan Africa. In recent years, there has been a drastic rise in multidrug resistance within this lineage, including fluoroquinolone resistance, a first line antimicrobial …
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A Multifaceted Approach to Study Salmonella Typhimurium Pathogenesis
… vivo expression technology) system to select S. typhimurium genes that are specifically induced in the host during infection. This unique IVET selection was done in hopes of finding genes specifically induced in the aorta of BALB/c mice. In this selection, several genes important for the …
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Periplasmic determinants of virulence in Salmonella enterica
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that is capable of causing systemic infection in mammals. Its normal course of infection brings this organism into the diverse environments of the stomach, the small intestine, the large intestine, and in the case of …
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Cloning and characterization of neuraminidase from Salmonella typhimurium LT-2 and its relationship to neuraminidase from other bacteria
… The gene encoding NANase (nanH) from Salmonella typhimurium has been cloned and its protein product purified. The purified NANase is 41.3 kD with an isoelectric point of approximately 9.0. The enzyme does not require Ca$\sp{++}$ for maximal activity and is not affected by EDTA or EGTA. S. …
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Characterization of the grvA and grvB Anti -Virulence Genes Encoded by the Gifsy-2 and Gifsy -1 Bacteriophages of Salmonella Typhimurium
… fever in a variety of hosts. The serovar S. typhimurium causes a typhoid-like fever in mice which serves as an animal model of enteric fever. The lambdoid phages, Gifsy-1 and Gifsy-2, contribute significantly to S. typhimurium virulence. We have been studying biology of these phage to …
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House Fly (Musca Domestica L.) Temporal and Spatial Immune Response to Streptococcus Pyogenes and Salmonella Typhimurium: Role of Pathogen Density in Bacterial Fate, Persistence and Transmission
… Streptococcus pyogenes and Salmonella typhimurium SR11 within the fly alimentary canal both spatially via epifluorescence microscopy and quantitatively via culture-recovery. Adult house flies were fed known amounts of bacteria (high or low dose), and were dissected to remove the entire …
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REGULATION AND EXPRESSION OF AMYLOID CURLI IN SALMONELLA INFECTION
… regulators of biofilm expression in vivo. S. Typhimurium uses signals from the host environment to enhance its pathogen fitness during infection. Together, these studies provide a link between biofilm associated infections and autoimmune responses in the host. In these studies, we sought to …
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Human enteroids as a model for infectious disease
… Salmonella enterica subspecies enterica serovar Typhimurium (S. Typhimurium). Enteric HAdV are notoriously difficult to culture in vitro despite being excreted in high numbers from infected individuals. We found that both prototype strains and clinical isolates of enteric and nonenteric HAdVs …
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Modelling the interactions of Salmonellae with the human host using stem cell-derived intestinal organoids and macrophages
… serovars (NTS) (e.g. S. enterica serovar Typhimurium (S. Typhimurium), S. enterica serovar Enteritidis (S. Enteritidis)) are responsible for over 93 million infections and ~155,000 deaths worldwide per year, the majority of which are thought to be food-borne infections. NTS infections …
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A Bifunctional Nanocomposites Based Electrochemical Biosensor for In-field Detection of Pathogenic Bacteria in Food
… Escherichia coli O157:H7 and Salmonella Typhimurium, in foods. The possible presence of pathogenic bacteria in foods has always been a great threat to the wellbeing of people and the revenue of food companies. Therefore, the demand for rapid and sensitive methods to detect foodborne …
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