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Showing 1 to 3 of 3 for “"Rtcb"”.
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Biochemical and structural studies of RNA damage and repair in bacteria
… scaffold proteins. One family of RNA ligases, RtcB, is widely distributed among the domains of life and has been implicated in tRNA splicing in eukaryotes and archaea. However, the role of RtcB in bacteria remains elusive. Bacterial RtcB may be involved in RNA repair but the complexity of RNA …
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Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases
… use a “direct ligation” pathway carried out by RTCB, an enzyme completely unrelated to Trl1. Because of these mechanistic differences, Trl1 has been proposed as a promising drug target for fungal infections.</p> <p>In this study, I systematically tested whether Trl1 meets the key criteria for a …
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Characterization of RNA damage and repair in bacteria
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01