Global ETD Search
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Showing 1 to 2 of 2 for “"Rpn11"”.
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Decoding Mitochondrial Heteroplasmy: Illuminating Regulatory Pathways via Rpn11, Mocs3, and Beyond
… ubiquitin-pathway-like E1 activating enzyme, and RPN11, a subunit of the 26S proteasome complex, showed consistent effects in different cell lines. I then investigated the in vivo effects of Mocs3 and Rpn11 and discovered that removing one genomic copy of these two genes significantly reduces the …
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Structural and biophysical analysis of the proteasomal deubiquitinase, UCH37
… enzymes, UCH37 and USP14, and one intrinsic, Rpn11, to remove polyubiquitin chains from substrate proteins as they are unfolded and translocated into the proteolytic core of the proteasome, where proteins are cleaved into small peptides and then released for recycling by the cell. UCH37 …