Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Rpb1"”.
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The largest subunit of RNA polymerase II (rpb1) as a phylogenetic marker of seed plant species
… elucidate unanswered phylogenetic issues using rpb1 genes from twenty-six land plant species (8 gymnosperm species, 17 angiosperm species and Psilotum, a fernally, as the outgroup). The sixteen rpb1 genes which were sequenced in this study had very similar lengths and contained no base …
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Sumoylation of RNA Polymerase II Regulates Transcription in Saccharomyces cerevisiae
… While it was previously reported that Rpb1, the largest subunit of RNA polymerase II (RNAPII), is sumoylated following UV-stress, our lab has shown that Rpb1 is also sumoylated under normal growth conditions. Here, we show that sumoylated Rpb1 is mostly associated with chromatin, …
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The functions of the RNA polymerase II CTD in transcription and RNA processing
… RNAs (ncRNAs), is composed of 12 subunits. Rpb1, the largest subunit with catalytic polymerase activity, possesses a unique c-terminal domain (CTD) that consists of tandem heptad repeats with the consensus sequence of Tyr-Ser-Pro-Thr-Ser-Pro-Ser (Y1S2P3T4S5P6S7). Somewhat reflecting the …
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OROPOUCHE VIRUS DISRUPTION OF HOST CELL FUNCTIONS: PYROPTOSIS INDUCTION AND TRANSCRIPTIONAL SUPPRESSION
… the levels of the C-terminal domain of the RPB1 subunit of RNA Polymerase II (RNAPII), primarily the hyperphosphorylated llo form. Wild-type (wt) OROV infection decreases RPB1 independently of proteasomal degradation, suggesting an impairment in RPB1 synthesis. Additionally, the …
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Molecular evolution of the RNA polymerase genes and the phylogeny of seed plants
… subunit of RNA polymerase I, II and III (rpa1, rpb1 and rpc1, respectively) as a new line of evidence from the nuclear genome to address seed plant phylogeny. These protein-coding genes refute the Anthophyte hypothesis (which relates Gnetales and angiosperms) and support the Gnepines hypothesis …
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Transcription Coupled DNA Repair in Saccharomyces Cerevisiae: the Interplay of Facilitators and Repressors
… interacts with Rpb4/7. Spt5 also interacts with Rpb1 and Rpb2, two largest subunits of RNAP II, at the clamp, protrusion and wall domains. Deletion of Spt5 KOW4-5 domains decreases transcription elongation and derepresses TCR. Our findings suggest that Spt5 is a key coordinator for holding the …
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Elongación transcripcional en Saccharomyces Cerevisiae influencia en el control del ciclo celular y nuevas herramientas para su estudio "in vivo"
… por doce subunidades codificadas por los genes RPB1 a RPB12. Todos ellos son esenciales excepto RPB4 y RPB9 (Woychik and Young, 1989).Las subunidades Rpb1 y Rpb2 son las de mayor tamaño y las más conservadas evolutivamente. La subunidad Rpb1 posee un dominio carboxilo terminal (CTD, del inglés …
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Mechanisms of recruitment of the CTD phosphatase Rtr1 to RNA polymerase II
… (CTD) of the RNA polymerase II (RNAPII) subunit Rpb1 must exist in a hypophosphorylated state prior to forming a competent transcription initiation complex. However, during transcription, specific kinases and phosphatases act on the RNAPII CTD to regulate its phosphorylation state, which serves …
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Changes in the Rpb3 Interactome Caused by the Deletion of RPB9 in Saccharomyces cerevisiae
… The most prominent of these hits are Rtr1, an Rpb1 C-terminal domain phosphatase linked to transcription termination, and Sen1, an RNA/DNA nuclease that terminates transcription. In addition, this mutant showed no interaction with Mtd1, an interaction that is present in the wild type. In all …
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Filogenia e identificação de espécies de Fusarium, Neocosmospora e Geotrichum associadas à cultura da batata-doce
… filogenética das regiões gênicas TEF1, RPB2, RPB1 e CAM e no estudo da morfologia das estruturas reprodutivas, o que resultou em um total de 51 isolados. A identificação das espécies de Geotrichum foi baseada nas análises filogenéticas da região amplificada do rDNA-ITS e do domínio D1/D2 da …
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A monograph of the freshwater ascomycete family Annulatascaceae: a morphological and molecular study
… were variable. Addition of other genes (e.g. RPB1, TEF1α) to future analyses may increase confidence at both basal and distal nodes for this clade. A second limitation of this study was taxonomic coverage using sequence data. Though great effort was given to collecting, not all Annulatascaceae …
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Biomolecular condensation of intrinsically disordered regions in P. falciparum and H. sapiens transcription factors
… sequence characteristics of the P. falciparum RPB1 C-terminal domain (PfRPB1-CTD) that suggest a functionally divergent role in biomolecular condensation. This work demonstrates that the PfRPB1-CTD, as well as a panel of GTF-IDR fusion proteins, including P. falciparum (Pf) and Homo sapiens …
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RNA Polymerase II control in the changing transcriptional landscape
… is investigated. The largest subunit of Pol II, RPB1, has a conserved C-terminal repeat domain (CTD) that contains 52 heptapeptide repeats and functions as a scaffold where transcription regulators bind. This unstructured 'tail' undergoes phosphorylation changes during the transcription cycle, …
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A circumscription of the earth tongue fungi class Geoglossomycetes
… as well as the protein-coding genes MCM7 and RPB1, to examine the largest dataset of Geoglossomycetes (24 total taxa, 15 ingroup species) publicly available at that time. In this study, we presented evidence showing that the viscid earth tongue, Geoglossum glutinosum, formed a separate and …