Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Rnd3"”.
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The role of Rnd3 in kidney morphogenesis and function
… of ADPKD phenotypes, a novel mouse model Rnd3tm1b(EUCOMM)Hmgu was generated. Rnd3 is an atypical member of the Rnd subgroup of the Rho family of GTPases and has a role in actin cytoskeleton reorganisation, cell cycle progression, and cell migration. The characterisation of the kidney …
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Regulation of apoptosis and desmosomes by RhoE
… thesis focuses on one member of the family, RhoE/Rnd3, and the analysis of the role it plays in the regulation of proliferation, differentiation, apoptosis and cell-cell adhesion in the epidermis. Use of RNA interference to specifically ‘knock-down’ expression of RhoE has led to the discovery of a …