Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 25 for “"Risperidone"”.
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Estudo comparativo entre antipsicóticos atípicos no tratamento da esquizofrenia e sua influência na qualidade de vida dos pacientes
… of atypical antipsychotics, olanzapine and risperidone on the quality of life and on their adverse effects in schizophrenic patients. For this we analyzed the quality of life of patients with implementation of EuroQol-5D-3L instrument and performing biochemical and hormonal tests, blood …
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Antipsychotic drugs for the treatment of acute schizophrenia after the first episode
… use, the difference between aripiprazole and risperidone was statistically significant for diminished sexual desire (p=0.01). Long term APDs use, the difference between aripiprazole and ziprasidone was significant for increased duration of sleep (p=0.003), rigidity (p=0.02), erectile …
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A associação do ganho de peso com o uso de quetiapina ou risperidona em pacientes com esquizofrenia: uma revisão sistemática
… the most commonly used nowadays. Among them, risperidone and quetiapine, have proven to be effictive in the treatment of schizophrenic patients, with an intermediate risk for weight gain.Objective: To identify through systematic review of the medical literature publications about the use of …
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Development of a Novel Drug Delivery System Based on Conducting Polymers
… to provide for the controlled release of risperidone. Due to the inherent properties of ICPs, electrical stimulation can be used to alter the redox state of PPy, which in turn can modify the release rate of drug. A validated, specific, stability indicating high performance liquid …
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METABOLIC ADVERSE EFFECTS INDUCED BY SECOND GENERATION ANTIPSYCHOTIC DRUGS IN PEDIATRIC PATIENTS: PHARMACOGENETIC PROFILING AND MECHANISTIC ANALYSIS OF GENETIC VARIANTS EFFECT IN VITRO MODELS
… behavioural disturbance who are prescribed SGAs (risperidone and aripiprazole), we have assessed the association of pharmacodynamics genetic variants with the occurrence of changes in body mass index (BMI) Zscore. This allows us to evaluate if the presence of specific variant alleles increases or …
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Epidemiology, diagnosis and aspects of treatment in persons with serious mental illness and co-occurring substance use disorders
… second in a systematic review, the efficacy of risperidone versus other antipsychotics for people with a dual diagnosis. Methods: This thesis consists of secondary analyses of two datasets (datasets#1 and dataset#2) and a Cochrane systematic review of existing randomised trials. Dataset#1 …
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Multiple Memory Systems in People With Schizophrenia: Possible Effect of Atypical Anti-Psychotic Medications
… that affect the dorsal striatum (e.g., risperidone), have altered performance on the PCL, and those treated with antipsychotics that affect the PFC (e.g., clozapine), have altered performance on the IGT. We tested the hypothesis that patients with schizophrenia treated with olanzapine …
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Variability in Pricing of Generic Antipsychotic Medications Used in the Treatment of Schizophrenia at Community Pharmacies in the Kansas City Metropolitan Area
… second-generation antipsychotic medications (risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole) recommended for first line therapy in the treatment for schizophrenia is lacking. Pharmacy-level variability in retail cash pricing for five generically available second-generation …
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The Discriminative Stimulus Properties of the Atypical Antipsychotic Clozapine in C57BL/6 Mice
… that the atypical antipsychotics olanzapine, risperidone, ziprasidone but not the typical antipsychotic haloperidol fully substitutes for clozapine. The present study demonstrated that the atypical antipsychotics quetiapine, sertindole, zotepine, iloperidone, melperone fully substituted for …
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A Description of Psychotropic Medication Use in Institution and Community Settings in Ontario.
… and the most common antipsychotics were risperidone, quetiapine and olanzapine.
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Exploration of cognitive and neurochemical deficits in an animal model of schizophrenia. Investigation into sub-chronic PCP-induced cognitive deficits using behavioural, neurochemical and electrophysiological techniques; and use of receptor-selective agents to study the pharmacology of antipsychotics in female rats.
… by sub-chronic administration of clozapine and risperidone, but not haloperidol. The effect of PCP was also shown to be more robust in female rats compared to males. A deficit in set-shifting ability was also observed in isolation reared rats. However, the deficits produced by PCP were more …
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Psichikos sutrikimų tyrimas ir jų gydymo įvertinimas klausos sukelto potencialo P300 metodu /
… the influence of atypical antipsychotics risperidone and quetiapine and such nonpharmacological methods as electroconvulsive therapy and metaglossotherapy on the changes of information processing in the auditory system using event-related potential P300 recording and analysis method. …
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Characterising the functional homology of central nervous system drug targets in larval zebrafish (Danio rerio)
… three antipsychotics (aripiprazole, clozapine, risperidone). Chapter 1 reviews the occurrence, mechanisms of action, and environmental relevance of CNS-active pharmaceuticals, identifying key knowledge gaps in linking molecular conservation to ecological outcomes. Major neurotransmitter systems, …
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Investigation of the Effects of Antipsychotics on CNS Insulin-mediated Brain Glucose Uptake using 2DG Autoradiography
… four additional APs (haloperidol, raclopride, risperidone, and aripiprazole) with varying receptor affinities. We determined that all APs, regardless of class, also induced central insulin resistance in regions responsible for reward processing, motivation, metabolism, as well as cognition. …
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Understanding the impacts of antipsychotic pharmaceuticals on behaviour in fish
… profiles. Among these atypicals, quetiapine, risperidone and aripiprazole produced the most extensive changes across key regions of interest. These agents were later assessed on the attraction-aversion axis, finding reliable changes to feeding behaviour, including a reduction in feeding …
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The impact of antipsychotic drugs on the expression of genes associated with obesity
… tested but only in one gene when treated with risperidone. Treatment with 5-HT promoted an increase in mRNA expression of some obesity-related genes, which was similar to the treatment with 0.25 μg/ml clozapine although this effect was not apparent with a combination of clozapine and 5-HT. …
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The gut microbiota as a contributing factor to antipsychotic-induced weight gain and metabolic dysfunction
… can attenuate certain aspects of olanzapine and risperidone–induced metabolic dysfunction, in particular fat deposition and adipose tissue inflammation. Mechanisms underlying this novel link appear to involve energy utilization via expression of lipogenic genes as well as reduced inflammatory …
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Quantitative assessment of the pharmacotherapy of biopolar disorder and schizophrenia
… The differences in effects between lithium and risperidone were -2.79 (95% CI -4.22 to -1.36) in favour of risperidone with respect to symptom severity improvement and -0.76 (95% CI -1.11 to -0,41) on the basis of reduction in global severity of disease. Symptom and global severity was at least …
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Neonatal Phencyclidine (PCP) induced deficits in rats: A behavioural investigation of relevance to schizophrenia.
… PCP treatment were reversed following acute risperidone but not haloperidol. Finally, the temporal profile of this treatment regime was investigated and the male and female animals were tested on PND 190 and PND 365. The animals did not have any challenge dose of PCP during their testing …
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Development of implantable devices for schizophrenia treatment
… is commonly prescribed to treat schizophrenia is risperidone (RIS). This drug is administered through the oral route (e.g. tablets). Accordingly, the drug is exposed to first-pass metabolism and enzymatic degradation in the gastrointestinal tract. Besides, it also can be administered as …
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