Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Ring-closing olefin metathesis"”.
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Synthesis of Taxol™ Analogs as Conformational Probes
… Difficulties were encountered with the key ring-closing metathesis strategy, suggesting that a more flexible and efficient macrocyclization method will be needed to synthesize additional macrocyclic analogs.
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Towards the Total Synthesis of Antascomicin B. Efforts to Construct the C1-C21 Fragment
<p>Antascomicin B is a macrolide isolated from a strain of <em>Micromonospora</em>. It possesses structural similarities to FK506 and rapamycin and exhibits potent binding ability to FKBP12. Recent reports suggest that small molecule ligands of FKBP12 possess potent neuroprotective and …