Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Ring distortion"”.
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Chemical diversification of the natural products quinine, abietic acid and pleuromutilin by ring distortion
Ring distortion reactions directly alter the core ring systems of small molecules and can lead to striking changes in molecular structure. Strategic application of ring distortion reactions to complex molecules, such as natural products, is an effective method for the generation of compounds that …
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Ring distortion of the alkaloid sinomenine and novel prodrug approaches to broad-spectrum antibiotics
… as it addresses the major limitation of discovering new broad-spectrum antibiotics: passage across the outer membrane, and ultimately accumulation. The chapters herein emphasize the importance of combating antibiotic resistance, specifically against Gram-negatives, and provide actionable …
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Structural behaviour of concrete segmental lining tunnels: towards design optimisation
The deployment of engineering models and design methods divorced from the effect that mechanised shield tunnelling with tunnel boring machines (TBMs) has on concrete segmental linings (CSLs) can lead to either material waste or structural damage within the tunnel design life. Most research to date …