Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"Right ventricle"”.
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Magnetic resonance imaging of the right ventricle in human pulmonary hypertension
… devastating illness which results in progressive right ventricular (RV) failure and early death. RV function determines survival in all patients with PH but it is difficult to measure accurately using existing clinical techniques. The choice and design of the experiments in this thesis was driven …
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Effect of Long-Term Hypoxia on Myocardial Alpha1- Receptors
… developmental process with both fetal left ventricle(LV) and fetal right ventricle(RV) having significantly more binding sites than respective adult ventricles. We also demonstrated that the positive inotropic response to the α<sub>1</sub>-adrenergic agonist phenylephrine did not differ …
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Magnetic resonance imaging studies of cardiac changes in diabetic and hypertensive rats
… and functional changes in the left and right ventricles following induction of diabetes in streptozotocin-treated rats. The effects of the angiotensin-converting enzyme inhibitor captopril upon such changes were also investigated. Finally, the MRI methods were also used to characterize …
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Tetralogy of Fallot Surgical Repair and Associated Right Ventricular Remodeling
… suffer from complications related to a failing right ventricle. Follow-up studies evaluating TOF repair strategies suggest an association between the type of surgical repair strategy and late right ventricular health. However, surgical practices remain unchanged and led by institution-level …
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RUOLO DELLA STIMOLAZIONE VAGALE SULLA PROLIFERAZIONE DEI FIBROBLASTI CARDIACI IN VIVO IN MODELLO ANIMALE DI FIBRILLAZIONE ATRIALE.
… Angiotensin II receptor antagonist. The level of right ventricle was almost two time compare with both atria analysis or left ventricle analysis, the VNS increase the level of of mRNA levels for ventricular and atrial α1 (I) and α1(III) procollagen in the right ventricle also in the sinus rhythm …
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Der Einfluss der hämodynamischen Druckbelastung des rechten Ventrikels auf die Expression pro- und anti-inflammatorischer Zytokine bei Neugeborenen : eine tierexperimentelle Untersuchung
The function of the right ventricle is an important parameter to evaluate the prognosis of neonates suffering from complex congenital heart defects, pulmonary stenosis or pulmonary hypertension. In these patients the right ventricle is often exposed to a major chronic pressure overload. Even though …
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Studies in right ventricular function: Employing the conductance catheter method for ventricular volume determination
The importance of quantifying right ventricular (RV) function has become clear in recent years. Following adult cardiac surgery right ventricular dysfunction has emerged as a significant cause of morbidity and mortality, particularly after transplantation and during left ventricular (L V) assist …
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ΣΥΜΒΟΛΗ ΕΙΣ ΤΗΝ ΜΕΛΕΤΗΝ ΤΩΝ ΜΕΤΑΒΟΛΩΝ ΤΗΣ ΑΙΜΑΤΩΣΕΩΣ ΤΟΥ ΜΥΟΚΑΡΔΙΟΥ ΕΠΙ ΦΥΣΙΟΛΟΓΙΚΩΝ ΚΑΙ ΕΣΤΕΝΩΜΕΝΩΝ ΣΤΕΦΑΝΙΑΙΩΝ ΑΓΓΕΙΩΝ ΚΑΤΟΠΙΝ ΑΥΞΗΣΕΩΣ ΤΗΣ ΚΑΡΔΙΑΚΗΣ ΣΥΧΝΟΤΗΤΟΣ
… OF THE ANTERIOR AND POSTERIOR WALL OF THELEFT VENTRICLE, THE DIAPHRAGM AND THE RIGHT VENTRICLE. THE PRESSURE OF THE LEFT VENTRICLE AS WELL AS THE SYSTOLIC AND MEAN PRESSURE OF THE AORTA DID NOT CHANGE SIGNIFICANTLY BETWEEN THE THREE PHASES OF THE EXPERIMENT. ONLY THE DIASTOLIC PRESSURE OF THE …
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Characterisation and functional analysis of a novel msp domain – containing protein, MOSPD1
… Mospd 3 gene trap neonates displayed a right ventricle defect characterised by a thinning of the right ventricle wall. The function of Mospd 1 is not known. Whilst Mospd 3 is mammalian specific Mospd 1 is conserved in all vertebrates including Danio rerio (zebrafish). The aims of this …
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The Angiotensin Receptor (AT₁) Inhibitor, Losartan, Slows Post-Natal Thickening of the Left Ventricle
… angiotensin system (RAS) in the mammalian left ventricle regulates growth of heart tissue in response to pressure-overload. Upon parturition, the mammalian left ventricle (LV) experiences pressure overload to which it responds by rapid growth, becoming thicker than the right ventricle (RV) in a …
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Control of Cardiac and Limb Development by the bHLH Transcription Factors DHAND and eHAND
… dHAND and eHAND null embryos die from defects in right ventricular and placental development, respectively. Therefore, we have investigated three aspects of HAND gene biology. Firstly, in order to determine the mechanisms that establish chamber identity during cardiac development, we have …
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The bone cement implantation syndrome - epidemiology, pathophysiology and prevention
… was accompanied by significant decreases in the right ventricle ejection fraction (RVEF), cardiac index (CI), and stroke volume index (SVI), with the reductions often being sustained throughout the surgical procedure. Gas exchange abnormalities were regularly observed in the forms of decreasing …
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Comparative Analysis of Pressure Mapping Methods in Repaired Tetralogy of Fallot: Four-Dimensional Blood Flow Hemodynamics Assessment and Development of a Novel Pressure Mapping Tool
… TOF repair (rTOF) and can impact the load on the right ventricle, blood flow pressure, and pulmonary hemodynamics. Pressure mapping, obtained through 4D-flow magnetic resonance imaging (4D-flow MRI), has been applied to identify abnormal heart hemodynamics in CHD. Hence, the aim of this research …
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Correlating with Local Variation in Collagen Level and Mechanical Properties of the Heart Tissues
… experimentally obtained images from the left and right ventricles to develop a model for calculating the shear modulus, Young's modulus, and the Poisson's ratio of the ventricles leading to obtaining the constitutive matrices for each specimen. Tissue behavior was quantified under three different …
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Feasibility of Echocardiographic Particle Image Velocimetry for evaluation of cardiac left ventricular filling function
… impairment of performance in either the left or right ventricle of the heart. Although there has been a marked increase in study of this disease, there is still an apparent difficulty to diagnose patients. Flow visualization techniques have been commonly employed to study the development of these …
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Yap and Taz Are Required For Neural Crest-Derived Cardiovascular Development
… (VSD), tetralogy of Fallot (TOF), double outlet right ventricle (DORV), and cardiac valve aberrations, varyingly between embryonic day (E) 14.5, E16.5, and E18.5. Cell apoptosis, proliferation, and smooth muscle differentiation were unchanged in <em>Yap<sup>+/-</sup>; Taz<sup>-/-</sup> </em>CKO …
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The development of a remotely expandable anastomosis device for use in paediatric cardiothoracic surgery
… first study, the device was implanted into the right ventricle of a cadaveric pig to determine any potential impediments that would need to be addressed for implantation into live animal models. The second implantation was carried out on 6 piglets, successfully establishing CPB procedures;The …
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Regional Mechanical Properties and Microstructure of Ovine Heart Chambers
… anterior and posterior portions of the left and right ventricles, atria, and appendages underwent biaxial mechanical testing. A Fung-type strain energy function was used to fit the experimental data. Tissue behavior was quantified based on the magnitude of strain energy, as an indicator of tissue …
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Cardioprotective effects of Glucagon-like Peptide 1 (GLP-1) and their mechanisms
… ischaemia reperfusion injury in the left ventricle in humans. It has been suggested from some animal research that this protection may be mediated through the pathway of ischaemic conditioning, of which the opening of the mKATP channel is a key step. Furthermore, it is uncertain whether …
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Cardiovascular magnetic resonance and right ventricular angiography in assessment of right ventricular volumes, function and wall motion abnormalities in arrhythmogenic right ventricular cardiomyopathy: a comparative study
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy characterised by structural changes to mostly the right ventricle (RV) that predisposes to ventricular arrhythmias heart failure and sudden cardiac death. ARVC is diagnosed using the 2010 Task Force …
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