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Showing 1 to 2 of 2 for “"Ribosome associated quality control"”.
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Structure and Function of the ER-Membrane Complex
… degradation for the first time. I find that the quality control process utilises machinery shared with cytoplasmic ribosome associated quality control (RQC). I proceed reproduce my observations with parallel experiments for CFTR$\Delta$F. In order to develop our mechanistic understanding of the …
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Insights into the mechanisms of translation surveillance using constitutive RNA binding ASC-1 complex mutants
… stretches of problematic or damaged mRNA, ribosomes can slow, stall, and collide. Although ribosome stalling and collisions can be caused by numerous translation stresses, from mRNA damage to amino acid starvation, collided ribosomes exist abundantly even in the absence of overt translation …