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Showing 1 to 2 of 2 for “"Ribonuclease III"”.
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Regulation of escherichia coli ribonuclease III by the bacteriophage T7 protein kinase
Ribonuclease III (RNase III) is a double-stranded-RNA-specific nuclease of Escherichia coli. RNase III functions as a homodimer. The 25.6 kDa subunit contains two domains, a 148 residue catalytic domain and a 78 residue double-stranded-RNA-binding domain (dsRBD). RNase III is involved in the …
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Understanding Recognition of Primary MicroRNAs by Human Drosha/DGCR8
… positions within these substrates to perform ribonuclease activity. My thesis work focuses on how the Drosha/DGCR8 complex recognizes primary microRNA structures and determines their processing sites, thereby regulating the initiation of microRNA biogenesis. Past biochemical and structural …