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Showing 1 to 12 of 12 for “"Rhodopsins"”.
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Rhodopsins as light-detectors: Of visual pigments and human beings
Rhodopsin is the light-sensitive pigment of the photoreceptor cells of higher organisms. Photon absorption by rhodopsin initiates a biochemical amplification cascade that results in an electrical signal. Rhodopsin is composed of the protein opsin, and the chromophore retinal, linked to it by a …
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Expression of microbial rhodopsins in retinal neurons with subcellular targeting motifs: for the study of the structure/function of aii amacrine cells and for vision restoration
<p>Protein-targeting motifs serve as addresses for subcellular protein localization. This feature of targeting-motifs was used to study the retina. The first part of the dissertation reports in the axonless spiking AII amacrine cell of the mammalian retina a dendritic process sharing organizational …
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Respuestas fúngicas a señales ambientales: Funciones de las proteínas CarO, OpsA, CutA y AcyA en Fusarium fujikuroi
… this Thesis is focused on the study of Fusarium rhodopsins, membrane-embedded photoreceptors using retinal as chromo-phore, found in all major taxonomic kingdoms. Rhodopsins play well-known functions in different biological systems, but their roles in fungi remain unknown. The filamentous fungus …
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Studies of G-Protein Coupled Receptors Incorporated Into a Novel, Nanoscale, Membrane-Mimetic System
… activity of G protein coupling for single rhodopsins sequestered in individual NABBs was nearly identical to that of two rhodopsins per NABB under conditions where stoichiometry and orientation could be inferred by electron microscopy imaging. Thermal stability of rhodopsin and CCR5 in …
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Structure-function relationship of archaeal rhodopsin proteins analyzed by continuum electrostatics
… types are found in the family of archaeal rhodopsins, namely the proton pump bacteriorhodopsin, the chloride pump halorhodopsin and the photoreceptor sensory rhodopsin II. For these three membrane proteins, high-resolution X-ray structures are available, allowing a theoretical investigation …
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Cloning of a <i>CHLAMYDOMONAS REINHARDTII</i> Marker into a RNA Interference Construct to Test Whether the Photoreceptor Chlamyrhodopsin Is Involved in Circadian Clock Resetting
… study the circadian clock in plants and animals. Rhodopsins are blue/green-light photoreceptors also found in <i>C. reinhardtii</i>. Chlamyrhodopsin (COP), the most abundant eyespot protein, was reported to have no role in the phototactic and photophobic responses in <i>C. reinhardtii</i>. Its …
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Elektrostatische Wechselwirkungen in komplexen Flüssigkeiten und ihre Beschreibung mit Molekulardynamiksimulationen
… des Retinalchromophors im Meta-III Zustand des Rhodopsins [R. Vogel, F. Siebert, G. Mathias, P. Tavan, G. Fan, M. Sheves, Biochemistry 42, 9863-9874 (2003)], der Chinone im bakteriellen Reaktionszentrum [M. Nonella, G. Mathias, M. Eichinger, P. Tavan, J. Phys. Chem. B 107, 316-322 (2003)] und …
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Kartierung der Bindungstasche des humanen Bittergeschmacksrezeptors hTAS2R10
… konnten auch bei der Agonisteninteraktion des Rhodopsins und des β2-adrenergen Rezeptors beobachtet werden. Die Ergebnisse dieser Arbeit helfen dabei die Wechselwirkungen zwischen Bitterstoffen und den Bittergeschmacksrezeptoren zu verstehen und geben erste Einblicke in die Entwicklung der …
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Vibrational spectroscopy of cation and anion channelrhodopsins
… with light by expression of specific microbial rhodopsins. Cation channelrhodopsins (CCRs) and anion channelrhodopsins (ACRs) have been demonstrated to activate and silence cell activity, respectively. In this dissertation, the molecular mechanisms of two channelrhodopsins are studied: a CCR …
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Metatranscriptomic and physiological analyses of proteorhodopsin-containing marine flavobacteria
… in marine Gammaproteobacteria, similar types of rhodopsins have been found in all three domains of life (archaea, bacteria, and eukaryotes). Recent studies have suggested that some flavobacteria showed a light-dependent increase in cell yield and growth rate of cultures grown in low carbon media. …
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Development of a saposin A based native-like phospholipid bilayer system for NMR studies
… proteins in Chapter 4. Two microbial rhodopsins, Anabaena sensory rhodopsin (ASR) and Natronomonas pharaonis sensory rhodopsin II (pSRII), were tested. The parameters for expression and purification of ASR were first screened for the optimal yield. Although incorporation of ASR …