Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Rhodium-catalysis"”.
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Studies in palladium and rhodium catalysis: synthetic strategies for C–C bond formation
This thesis concerns studies in palladium and rhodium catalysis for carbon-carbon bond formation. Chapter 1 involves the synergistic use of tetrabutylammonium acetate (NBu4OAc) with palladium catalysis to expand on the synthesis of dibenzofurans via C-H activation. Dibenzofuran and its derivatives …
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Cascade Transformations in Organic Synthesis: I. The Interception of Carbene Alkyne Metathesis Intermediates II. Photo-Activation of Hydrazones III. Organocatalyzed Cascade Conjugate Addition/Aldol Annulation of Organoboronates
… the multi-alkyne carbene cascade reaction under rhodium catalysis is discussed. Ten different diazoesters were synthesized and tested for cascade reactions. This transformation proved to be limited, since it only works for super engineered structures. It also reveals the possibility that carbene …
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NEW TRANSITION METAL CATALYSTS FOR CARBON-CARBON BOND FORMATION
… C-H insertion reactions is dominated by rhodium catalysis and robust intermolecular carbene C-H insertion reactions using copper are scarce. Using copper catalysis, a number of synthetically meaningful transformations were produced. Demonstrated are novel C-H insertions of carbenes in …
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Design and use of novel metal catalysts in organic synthesis
… focuses on the design and synthesis of novel dirhodium carboxylate catalysts, and their precursor ligands, for use as enantioselective catalysts in transformations of α-diazocarbonyl compounds. Chapter One focuses on the literature background over the past thirty years in transition …
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C(sp3)-H aminations under first row transition metal catalysis
… in the field have been with noble metal dirhodium carboxylate catalysts. These catalysts are highly reactive and have collectively displayed the ability to efficiently aminate benzylic, ethereal, and aliphatic C—H bonds. However, they are poorly chemoselective in the presence of …
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Transition metal-catalyzed olefin functionalization for highly regio-, enantio-, and chemoselective C–X bond formation
… is an important challenge in modern catalysis.1 This thesis specifically focuses on using transition metal-catalysis to form C–X bonds from C–C double bonds with high degrees of regio-, chemo-, and stereoselectivity. In chapter 1, a regiodivergent Rh-catalyzed hydrothiolation of allyl …
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Late-stage C(sp3)–H hydroxylation, amination, and methylation in nitrogen-containing molecules
… of these molecules via transition metal catalysis faced substantial challenges, as the strongly Lewis basic nitrogen is prone to bind to the Lewis acidic metal center, thereby either shutting down the catalysis or limiting functionalization to sites proximal to itself as a directing …
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Synthesis and reactivity of alpha-trialkylsilyl alpha-amino acids
… using an established protocol involving rhodium(II)-catalysed insertion reactions of alpha-trialkylsilyl alpha-diazo esters into N-H bonds of carbamates. As an extension to this procedure, it was accounted that a diastereoselective approach to N-protected alpha-trialkylsilyl alpha-amino …
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Novel synthetic methodology employing transition metal catalysed reactions of α-diazo-β-keto sulfonamides and α-cyano-α-diazoacetates; the impact of substituents on the reaction pathway
… and α-arylsulfonyl-α-diazoacetates employing rhodium and copper catalysts. While the α-diazo-β-keto sulfonamides were specifically designed to investigate rhodium- and copper-catalysed intramolecular C–H insertion, the α-cyano-α-diazoacetates and α-arylsulfonyl-α-diazoacetates probed …