Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"RhoA/ROCK"”.
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Effect of oncomodulin on cytoskeletal actin dynamics.
… intracellular actin dynamics in OHCs using RhoA/ROCK and LIMK/cofilin mediated pathways. We hypothesize that modulation of calcium signaling through mobile calcium buffers alters intracellular actin dynamics in OHCs. Early studies of OHC lateral stiffness and motility suggest that calcium …
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Differentiation Induces Dynamic Alterations in Mesenchymal Stem Cell Nuclear Architecture and Mechanotransduction
… by interplay between purinergic signaling and RhoA/Rock activity, and that baseline TGF superfamily signaling played a role in establishing cell contractility and mediating this load-induced chromatin remodeling response. Overall, this thesis identified novel signaling pathways and mechanisms …
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The effect of cAMP elevation on intracellular signalling pathways in prostate epithelial cells
… be recapitulated by reagents which inhibited RhoA/ROCK signalling, suggesting that cAMP elevation is able to inhibit RhoA activation via a PKA-dependent pathway. Additionally, cAMP elevation activated ERK1/2 and selective blockade of ERK signalling attenuated the effects of cAMP elevation on …
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The Non-genomic Signaling Pathways Mediated By G-protein Coupled Estrogen Receptor 1 (GPER) In Coronary Arteries
… coronary artery relaxation via inhibition of RhoA/Rho kinase pathway by cAMP downstream targets: the exchange proteins directly activated by cAMP (Epac) as well as PKA; and 4) activation of GPER potentiates coronary artery contraction by a G??/EGFR-dependent pathway. Isometric tension studies …