Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 107 for “"Rheumatoid arthritis (RA)"”.
-
Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent
… complexes are effective in the treatment of rheumatoid) arthritis (RA). Increasing the amount of copper associated with low molecular mass ligands in plasma helps to alleviate the symptoms of rheumatoid arthritis. Low molecular weight ligand, …
-
Joint effects: water exercise and manual therapies for arthritis
… investigated the relative effects of manual therapies and warm-water exercise on the health-related quality of life (HRQOL) of people with common arthritides (rheumatoid arthritis [RA] or osteoarthritis [OA]). The thesis comprised three linked clinical studies and a pilot study. The three …
-
Quantification and Molecular Characterization of Anti-citrulline Antibodies in Rheumatoid Arthritis
… immune system to distinguish self and non-self. Rheumatoid Arthritis (RA) is a systemic autoimmune disease that leads to joint destruction and affects more than 1.5 million adults (Centre for Disease Control). Auto-antibodies against citrullinated proteins (ACPA) are present in approximately …
-
Rheumatoid arthritis and atherosclerosis: common pathogenic mechanisms explored
This body of work draws on parallels between the pathogenesis of rheumatoid arthritis (RA) and atherosclerosis. The pathogenesis and genetic basis of both diseases are described and compared. I describe how a polymorphism of the CX3CR1 gene, which has been shown to have a protective association …
-
TRAIL mediated apoptosis in arthritis.
… and prolonged half life of inflammatory cells in rheumatoid arthritis (RA). A similar phenomenon is seen in malignancy. Therefore, defects in apoptosis pathways that have been proposed to contribute to the pathogenesis of malignancy may also be seen in RA. It has been reported by many studies that …
-
Presumption of perception: people with arthritis challenge the importance of pain in treatment
… mobilization on individuals with either osteoarthritis (OA) or rheumatoid arthritis (RA) and reported that joint mobilization was perceived by most participants to afford improvements in health-related quality of life (HRQOL). Some participants withdrew from the joint mobilization intervention …
-
Biomarkers for autoimmunie disease diagnosis in the public health sector: A systematic review and meta-analysis
Rheumatic heart disease (RHD), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are autoimmune diseases with drastic effects on quality of life. Diagnostic challenges remain, especially given the prevalence of these diseases among people of low socioeconomic status. The purpose of …
-
The biomechanical analysis of the hand in rheumatoid arthritis patients with MCP arthroplasty
Rheumatoid arthritis (RA) is a chronic inflammatory disease, causing extreme deformity, pain and swelling of joints, severely affecting quality of life. Arthroplasty has had considerable success in larger joints such as the hip. The most frequently used artificial finger joints rely on a silicone …
-
Mindfulness training in Physical Health: how might changes in emotional experience and/or regulation be implicated?
… and mental-health conditions, mindfulness training may represent a useful supplementary treatment approach. Rapidly increasing research has documented the ability of mindfulness-based interventions to improve health outcomes. However, often overlooked, are questions regarding the clinical …
-
Design of novel copper(II) based anti-inflammatory drugs for the elevation associated with Rheumatoid Arthritis
… able to alleviate inflammation associated with Rheumatoid Arthritis (RA). Serum copper levels are elevated in RA and it has been postulated that endogenous copper might have a protective function in chronic inflammatory conditions. In designing Cu(I1) anti-inflammatory drugs, one needs to know …
-
Sexual health in Rheumatoid Arthritis - a physiotherapeutic approach
The overall aim of this thesis was to study how persons experience the influence of Rheumatoid Arthritis (RA) on their sexual health and their experiences of communication about sexual health, in order to improve physiotherapy within the field of rheumatology. Sexual health is an integrated part of …
-
Investigating the function of TRAF1 in NF-κB activation
… necrosis factor receptor-associated factor (TRAF) proteins play an important role in mediating the activation of NF-κB. Dysregulation of NF-κB may be one of the potential causes of chronic inflammatory diseases. One member of the TRAF family, TRAF1, has been shown to increase the risk of …
-
Kinetic Characterization of the Protein Arginine Deiminase Family: Mechanistic and Inhibition Studies
… (PAD1, 2, 3, 4, and 6) that catalyze the post-traslational modification of peptidyl-arginine to peptidyl-citrulline in numerous protein substrates. This modification results in numerous physiological and pathophysiological changes that are believed to play a significant role in the onset and …
-
Understanding participation and its relationship with arthritis self-efficacy in a computer-supported community of practice for rheumatoid arthritis patients
… in a computer-supported community of practice (CSCoP) designed for rheumatoid arthritis (RA) patients to learn self-management. The study also explored the relationship between participation and Arthritis self-efficacy (as one of the desirable learning outcomes). In addition, the study …
-
Clinical and epidemiologic aspects of Rheumatoid Arthritis. Special emphasis on cardiovascular outcome and risk factors
Rheumatoid arthritis (RA) is a systemic disease, with an increased risk of co-morbidity from cardiovascular disease (CVD), in particular among those with severe disease. Environmental risk factors are of potential interest for both prevention and treatment of RA. Our aim was to examine changes in …
-
Clinical Significance of Rheumatoid Factor in Rheumatoid Arthritis
PURPOSE: Serum rheumatoid factor (RF) is important in the diagnosis and prognosis of rheumatoid arthritis (RA). This purpose of this study is to evaluate the clinical characteristics and treatments of RA according the presence of RF in Korean. MATERIALS AND METHOD: A retrospective analysis was …
-
Rheumatoid arthritis : a cognitive-behavioural intervention
… disease · status, and immune function in Rheumatoid Arthritis (RA), and the value of cognitive-behavioural intervention in improving the overall health status of such patients. Two related hypotheses were tested in a matched-random assigned two-groups design, with pre-, mid-, and …
-
LEVITY
… does it mean to <em>survive</em>? And to what travesties must we bear witness before collectively taking action to stop perpetuating toxic cycles which harm society’s most vulnerable? Beginning where the body, where language, ends (within the depths of ink itself—into the heartbeat drum of an …
-
Can curcuminoids be more effective than sulfasalazine for the treatment of rheumatoid arthritis?
Rheumatoid Arthritis (RA) is a debilitating, chronic autoimmune disease leading to progressive joint destruction. Current treatment includes methotrexate and sulfasalazine, however, side effects and tolerability are major limitations. Curcumin is a natural polyphenol obtained from Curcuma Longa …
-
The role of galectin-3 and galectin-9 in the chronic inflammation of rheumatoid arthritis
… (galectins) in fibroblasts from rhematoid arthritis patients. Synovial fibroblasts were found to differ significantly from bone marrow and skin fibroblasts with higher expression of galectin-9 and galectin-12 in synovial fibroblasts. Galectin-9 and galectin-3 expression was also examined in …
Page 1 of 6