Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Rheumatic heart disease (RHD)"”.
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The household economic impact of Rheumatic Heart Disease (RHD) in South Africa
Background: Rheumatic heart disease (RHD) remains a major public health concern in African countries due to the high rates of complications such as atrial fibrillation, stroke, infective endocarditis, and heart failure, all of which can result in premature death. In 2015, RHD was estimated to …
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The Economic Impact of Rheumatic Heart Disease (RHD) on the Health System of South Africa. A Cost of Illness Study.
Background Rheumatic Heart Disease (RHD) is a disease of poverty that is neglected in developing countries. The consequences of RHD are increasingly becoming huge economic burden to the health system and consecutively the government. Despite RHD being preventable, most of the RHD related deaths …
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Integrating the prevention and control of rheumatic heart disease into country health systems: a systemic review
… qualitative methods to be used when analysing rheumatic heart disease (RHD) prevention and care programmes. Part B is a literature review which expands on the protocol. An in-depth explanation of the disease process is presented in order to understand the multiple opportunities for preventing …
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Characterisation of phenotypes of inflammation, fibrosis and remodeling in chronic rheumatic heart disease using multiparametric cardiovascular magnetic resonance and autophagy markers
Background: Rheumatic heart disease (RHD), concomitant to valvular damage, heart failure, arrhythmias and pulmonary hypertension is the major source of cardiovascular morbidity and mortality in the young, predominantly in low- and middle-income countries (LMICs). We investigated the association of …
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Biomarkers for autoimmunie disease diagnosis in the public health sector: A systematic review and meta-analysis
Rheumatic heart disease (RHD), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are autoimmune diseases with drastic effects on quality of life. Diagnostic challenges remain, especially given the prevalence of these diseases among people of low socioeconomic status. The purpose of …
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The effect of distance to health facility on the maintenance of INR therapeutic ranges in rheumatic heart disease patients from Cape Town
… multicentre, hopital-based registry for rheumatic heart disease (RHD). This study made use of geographical information systems (GIS) as a tool to investigate the effect of distance on the maintenance of INR therapeutic ranges in RHD patients. Part B: elaborates on the background and …
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A study of determinants and prevalence of Rheumatic Heart Disease in Cape Town
Rheumatic Heart Disease (RHD) is a post-infectious immune disease ascribed to an interaction between a rheumatogenic strain of group A streptococcus, a susceptible host who lives in poor social conditions with limited access to medical facilities. The disease process begins with repeated group A …
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Polymeric Transcatheter Heart Valves
Rheumatic heart disease (RHD) is one of the main causes of heart disease in the emerging world. Once the disease has become symptomatic valve repair or replacement is the only treatment currently available. Commercial bioprosthetic valves (surgical and transcatheter) suffer from calcification and …
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A tri-phasic continuum model for the numerical analysis of biological tissue proliferation using the Theory of Porous Media. Application to cardiac remodelling in rheumatic heart disease
… aimed at describing the mechanotransduction of Rheumatic Heart Disease, in order to study and predict long-term effects of new therapeutic concepts to treat inflammatory heart diseases and ultimately, estimate their effectiveness to prevent heart failure. Attention is given to Rheumatic Heart …
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Clinical characteristics and outcomes of children with rheumatic heart disease: a global rheumatic heart disease registry (REMEDY) sub-analysis
Background: Despite Rheumatic Heart Disease (RHD) contributing to an estimated disease burden in 2019 of 40 million people and 285 500 deaths, few studies document the characteristics and outcomes in children. We undertook a sub-analysis of children from the multi-centre prospective two-year global …
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Growth, modelling and remodelling of cardiac tissue: a multiphase approach
Rheumatic heart disease (RHD) is identified as a serious health concern in developing countries, specifically amongst young individuals, accounting for between 250 000 and 1.4 million deaths annually. As such, the attention of this research is initially placed on the importance of the development …
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Investigation of circulatory and tissue-specific metabolomic biomarkers in valvular heart disease using mass spectrometry
… specific metabolic biomarkers in patients with rheumatic heart disease (RHD) and degenerative aortic stenosis (AS), compared to matched, healthy controls. The study hypothesis was that cardiac tissue obtained from heart valve biopsies from RHD and degenerative AS patients would have distinct …
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Genomic insights into Group A Streptococcus pathogenesis
… or undertreated GAS pharyngitis include Rheumatic Fever (RF) and Rheumatic Heart Disease (RHD). Despite evidence for the effectiveness of antibiotics such as penicillin, the burden of GAS remains high in low- and middle-income countries (LMICs) compared to high-income countries (HIC), …
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Outcomes of asymptomatic and symptomatic rheumatic heart disease
Rheumatic Heart Disease (RHD) is a leading cause of heart disease in children and young adults in the developing world, with significant associated morbidity and mortality. Early secondary prophylaxis may retard the deleterious progression from its antecedent, acute rheumatic fever to permanent …
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Standard echocardiography versus handheld echocardiography for the detection of subclinical rheumatic heart disease: A systematic review
Rheumatic heart disease (RHD) is a permanent heart valve condition resulting from an abnormal immune reaction to group A streptococcal (GAS) infection typically occurring in childhood. If left untreated, disease progression can result in irreversible heart valve damage, cardiac failure, stroke and …
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Communicable Diseases Epidemiology
… Epidemiology program, hosted in the Communicable Diseases Branch at Health Protection New South Wales (NSW). Presented in this bound volume are four research projects: an epidemiological study, data analysis study, outbreak response, and an evaluation of a public health surveillance system. I was …
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Communicable Diseases Epidemiology
… Epidemiology program, hosted in the Communicable Diseases Branch at Health Protection New South Wales (NSW). Presented in this bound volume are four research projects: an epidemiological study, data analysis study, outbreak response, and an evaluation of a public health surveillance system. I was …
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Communicable Disease Control in New South Wales and globally
Effective communicable disease control calls for a wide range of core public health competencies. In fulfilling the requirements of the Masters of Philosophy in Applied Epidemiology (MAE), I conducted projects in my placement at Health Protection New South Wales (NSW) between March 2014 and October …
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Communicable Disease Control in New South Wales and globally
Effective communicable disease control calls for a wide range of core public health competencies. In fulfilling the requirements of the Masters of Philosophy in Applied Epidemiology (MAE), I conducted projects in my placement at Health Protection New South Wales (NSW) between March 2014 and October …
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Temporal logic-based fuzzy decision support system for diagnosis of rheumatic fever and rheumatic heart disease
This is a collaboration project between the Nepal Heart Foundation (NHF) and the University of Greenwich (UoG), United Kingdom (UK). Our mutual aim, agreed at the outset, has been to analyse, design and develop a cost effective Clinical Decision Support System (CDSS) for diagnosis and recognition …
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