Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 43 for “"Rheumatic Heart Disease"”.
-
Clinical characteristics and outcomes of children with rheumatic heart disease: a global rheumatic heart disease registry (REMEDY) sub-analysis
Background: Despite Rheumatic Heart Disease (RHD) contributing to an estimated disease burden in 2019 of 40 million people and 285 500 deaths, few studies document the characteristics and outcomes in children. We undertook a sub-analysis of children from the multi-centre prospective two-year global …
-
Outcomes of asymptomatic and symptomatic rheumatic heart disease
Rheumatic Heart Disease (RHD) is a leading cause of heart disease in children and young adults in the developing world, with significant associated morbidity and mortality. Early secondary prophylaxis may retard the deleterious progression from its antecedent, acute rheumatic fever to permanent …
-
Computational modeling of the tissue mechanics in rheumatic heart disease patients
… measurements play a crucial role in advancing heart failure treatments, a leading global cause of mortality. Understanding the biomechanical characteristics of myocardial material behavior in both healthy and diseased hearts through finite element analysis offers valuable insights into cardiac …
-
The household economic impact of Rheumatic Heart Disease (RHD) in South Africa
Background: Rheumatic heart disease (RHD) remains a major public health concern in African countries due to the high rates of complications such as atrial fibrillation, stroke, infective endocarditis, and heart failure, all of which can result in premature death. In 2015, RHD was estimated to …
-
A study of determinants and prevalence of Rheumatic Heart Disease in Cape Town
Rheumatic Heart Disease (RHD) is a post-infectious immune disease ascribed to an interaction between a rheumatogenic strain of group A streptococcus, a susceptible host who lives in poor social conditions with limited access to medical facilities. The disease process begins with repeated group A …
-
Prevalence, and outcomes of Rheumatic Heart Disease in Ethiopia: a systematic review and meta-analysis
… While eradicated in other parts of the world, Rheumatic Heart Disease, nevertheless, remains one of the most common acquired heart diseases in low- to middle- income countries; in sub-Saharan Africa, there was an estimated prevalence of 10 persons per 1,000 population in 2015. In the Global …
-
Temporal logic-based fuzzy decision support system for diagnosis of rheumatic fever and rheumatic heart disease
This is a collaboration project between the Nepal Heart Foundation (NHF) and the University of Greenwich (UoG), United Kingdom (UK). Our mutual aim, agreed at the outset, has been to analyse, design and develop a cost effective Clinical Decision Support System (CDSS) for diagnosis and recognition …
-
Integrating the prevention and control of rheumatic heart disease into country health systems: a systemic review
… qualitative methods to be used when analysing rheumatic heart disease (RHD) prevention and care programmes. Part B is a literature review which expands on the protocol. An in-depth explanation of the disease process is presented in order to understand the multiple opportunities for preventing …
-
Standard echocardiography versus handheld echocardiography for the detection of subclinical rheumatic heart disease: A systematic review
Rheumatic heart disease (RHD) is a permanent heart valve condition resulting from an abnormal immune reaction to group A streptococcal (GAS) infection typically occurring in childhood. If left untreated, disease progression can result in irreversible heart valve damage, cardiac failure, stroke and …
-
Ethical challenges in obtaining informed consent for the genomic study of rheumatic heart disease: a qualitative study
… consent procedures for a genomic study on Rheumatic Heart Disease (RHDGen) at the University of Cape Town in South Africa. The main aim of the study was to understand the ethical challenges in obtaining informed consent in the RHDGen study. METHODS: We used a qualitative study methodology …
-
Stigma and African genomics research: An exploration of stigma associated with the genetic attribution of rheumatic heart disease
… mixed evidence about how genetic attribution of disease may impact on stigma. One theory, based on essentialism, argues that knowledge of genetic attribution may increase stigma, while attribution theory argues that bio-genetic explanations may result in individuals feeling a decreased sense of …
-
Towards Rheumatic Heart Disease vaccine development: Defining host immune responses to Group A Streptococcal infection in Cape Town
… of the bacteria, thus limiting post-sequelae diseases such as acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Due to the limited supply of penicillin, adherence issues and problems associated with the diagnosis of post-sequelae diseases, a vaccine is thought to be the way …
-
Ten-year propensity matched cohort analysis of mitral valve repair and replacement for rheumatic heart disease at Groote Schuur Hospital
Includes abstract. Includes bibliographical references.
-
The Economic Impact of Rheumatic Heart Disease (RHD) on the Health System of South Africa. A Cost of Illness Study.
Background Rheumatic Heart Disease (RHD) is a disease of poverty that is neglected in developing countries. The consequences of RHD are increasingly becoming huge economic burden to the health system and consecutively the government. Despite RHD being preventable, most of the RHD related deaths …
-
Characterisation of phenotypes of inflammation, fibrosis and remodeling in chronic rheumatic heart disease using multiparametric cardiovascular magnetic resonance and autophagy markers
Background: Rheumatic heart disease (RHD), concomitant to valvular damage, heart failure, arrhythmias and pulmonary hypertension is the major source of cardiovascular morbidity and mortality in the young, predominantly in low- and middle-income countries (LMICs). We investigated the association of …
-
The effect of distance to health facility on the maintenance of INR therapeutic ranges in rheumatic heart disease patients from Cape Town
… multicentre, hopital-based registry for rheumatic heart disease (RHD). This study made use of geographical information systems (GIS) as a tool to investigate the effect of distance on the maintenance of INR therapeutic ranges in RHD patients. Part B: elaborates on the background and …
-
Exploring how a genetic attribution to disease relates to internalised stigma experiences of Xhosa people with schizophrenia and rheumatic heart disease in South Africa
… Xhosa people with schizophrenia (n= 36) and rheumatic heart disease (n= 46). Additionally, a pilot study was conducted with another sample of schizophrenia (n= 65) and rheumatic heart disease (n= 55) patients to translate and adapt an internalised stigma of mental illness scale into isiXhosa. …
-
Optimisation of Surgical Timing in Rheumatic Mitral Valve Disease
Rheumatic heart disease is a consequence of Group A streptococcal infections, and disproportionately affects the world’s most disadvantaged people. Whilst the disease has been essentially eradicated from nonindigenous populations in Australia, Indigenous Australians continue to have some of the …
-
Sixteen year retrospective analysis of rheumatic and non-rheumatic heart disease patients undergoing valve procedures at Groote Schuur Hospital first incidence single aortic and mitral valve replacement
Rheumatic heart disease is still the most common cause of valvular heart lesions requiring replacement or repair procedures worldwide. In South Africa, where there is an interesting mix of first and third world dynamics, factors sustaining the epidemic of rheumatic disease are still commonplace. …
-
A tri-phasic continuum model for the numerical analysis of biological tissue proliferation using the Theory of Porous Media. Application to cardiac remodelling in rheumatic heart disease
… aimed at describing the mechanotransduction of Rheumatic Heart Disease, in order to study and predict long-term effects of new therapeutic concepts to treat inflammatory heart diseases and ultimately, estimate their effectiveness to prevent heart failure. Attention is given to Rheumatic Heart …
Page 1 of 3