Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Rhes"”.
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The Effects of Rhes on Opioid Analgesia
Rhes (Ras homolog enriched in striatum) has been identified as a novel monomeric G-protein involved in dopaminergic and other signaling in the striatum. Given the many effects of opioids that involve striatal circuitry, genetically engineered mice that are incapable of making Rhes (rhes-/-) and …
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Interactions of the Striatal Gene Rhes with the Dopaminergic System in Rodents
… are incapable of expressing the small G protein Rhes have been generated and have shown to have abnormalities in behaviors mediated by the striatum, a region in which Rhes is highly expressed. Moreover, conditions that result in dopamine supersensitivity and a breakdown in D1/D2 synergism in …
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The effects of Rhes, a striatal specific protein, on the expression of behavioral and neuropathological symptoms in a transgenic mouse model of Huntington's disease
… striatum and cerebral cortex. The Ras homolog Rhes is expressed very selectively in the precise brain areas affected by HD. Recent work using cultured cells suggests that Rhes may be a co-factor with mHtt in cell death. However, there is controversy as to whether cell death underlies the …
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Development and evaluation of Nuclear-Renewable Hybrid Energy System simulator with load following
… of Nuclear-Renewable Hybrid Energy Systems (N-RHES) with a focus on Load Following (LF) capabilities. The primary aim is to enhance the operational flexibility of nuclear reactors to adapt to dynamic power demands. A dynamic simulation tool was developed for different nuclear reactor …
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Exogenously-introduced Homing Endonucleases Catalyze Double-stranded DNA Breaks in Aedes aegypti
… breaks was inconclusive, assays used to test rHEs in Ae. aegypti were successful. Recognition sequences for various rHEs were introduced into Ae. aegypti through germline transformation, and imperfect repair at each of these exogenous sites was evaluated. In mosquitoes containing a single …
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Optimized clean hydrogen production using nuclear small modular reactor and concentrated solar power as a renewable energy source
… of a Nuclear-Renewable Hybrid Energy System (N-RHES). Optimization of design and functional variables/parameters, as complexity in system engineering, are considered as scenarios. The major results of this research is that multi-objective optimization provides recommended, operational scenarios …