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Showing 1 to 16 of 16 for “"Rhamnolipids"”.
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Controlling Microbial Multicellular Behaviors With Saccharide Derivatives
… <p>Pseudomonas aeruginosa is known to secrete rhamnolipids, a class of biosurfactants that plays an important role in maintaining the architecture of its biofilm and promoting its swarming motility. Here we show the ability of certain synthetic nonmicrobicidal disaccharide derivatives (DSDs) to …
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The physico-chemical and biological analysis of microbial biosurfactants (BSs) for applications towards cancer therapies, wound healing dressings and drug delivery
… characteristics of four selected BSs 95Dd rhamnolipids (BS1a), 95/90 rhamnolipids (BS1b), surfactin (BS2) and 1′, 4″-sophorolactone 6′, 6″-diacetate (BS3) were investigated through LC-MS, ATR-FTIR and surface tension analysis. This was followed by examination of cytotoxic activities …
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Chimera Ligand for Pili and Lectin A Protein Controls Antibiotic-Promoted Biofilm Formation, Swarming Motility, Tolerance and Persister Formation by Pseudomonas aeruginosa
… (or one of the receptors) that will bind to rhamnolipids and our synthetic agents, and upon binding, causing the bacterial activities. </p> <p>For quantification of polysaccharides, two efficient detection and quantification methods that make use of the negative charges of the alginate …
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Natural and Synthetic Ligand-Binding Induce Different Pilin Assemblies in vitro and Control P. aeruginosa Bioactivities in vivo, and Development of Bacterial-Motility Enabled Binding Assays
… P. aeruginosa by binding and sequestering rhamnolipids secreted by the bacterium, or reactivate the swarming motility of the bacteria by sequestering the synthetic inhibitor added in the hydrated gel. Separating the components of rhamnolipids reveal that monorhamnolipid is more active than …
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Efficiency of biosurfactants applied by means of electrokinetics
An evaluation of the efficiency of rhamnolipids (biosurfactants) used in electrokinetic remediation of soil contaminated with phenanthrene was presented. Bench scale tests were conducted using four experimental series in order to determine the feasibility and mechanisms of biosurfactant-enhanced …
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Isolation of a Pseudomonas aeruginosa Aspartate Transcarbamoylase Mutant and the Investigation of Its Growth Characteristics, Pyrimidine Biosynthetic Enzyme Activities, and Virulence Factor Production
… that the production of pigments, haemolysin, and rhamnolipids were significantly decreased from PAO1. Elastase and casein protease production were also moderately decreased. In the Caenorhabditis elegans infection model the nematodes fed the ATCase mutant had increased mortality, as compared to …
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Discovering the Biological Activities of Maltose Derivatives for Controlling Bacterial Multicellular Behaviors
… multicellular behaviors has been demonstrated. Rhamnolipids secreted by Pseudomonas aeruginosa are biosurfactants that are known to be essential for at least three multicellular behaviors of P. aeruginosa, biofilm formation, biofilm dispersion and swarming motility. Maltose derivatives, which …
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Influence of Indole and Mixed Culture Growth on Pseudomonas Aeruginosa Biofilm Structure
… of virulence mechanisms controlling pyocyanin, rhamnolipids, and elastase production, inhibiting quorum sensing.
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Anticancer and antibiotic leads from marine organis
… phenazines, six 2-alkyl-4-quinolones, and seven rhamnolipids. 2-Nonyl-4(1H)-quinolone and 2-(1-nonenyl)-4(1H)-quinolone displayed potent antimalarial activity, which was first reported here. Based on the metabolic profile of antibiotics from P. aeruginosa, chemical regulation and its impact on …
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Discovery and Characterization of Small Molecule Inhibitors of Biofilm Formation in Pseudomonas Aeruginosa
… research showed that production of excess rhamnolipids in P. aeruginosa PA01 caused dispersal of its biofilms. To identify small molecule inducers of rhamnolipid biosynthesis, in-house chemical libraries were screened using P. aeruginosa PS36, a strain possessing a chromosomally-encoded …
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Conversion of hydrocarbons to biosurfactants : an insight into the bioprocess optimisation of biosurfactant production using alkanes as inducers
… are subdivided into three main groups: rhamnolipids, sophorolipids and trehalolipids, named following their sugar moieties, respectively rhamnose, trehalose and sophorose. Biosurfactants exhibit attractive advantages over chemical surfactants. Examples of these are biodegradability, low …
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Sustainable treatment of oil contaminated waste: oil-based mud (OBM) drill cuttings and soil.
… the optimum washing condition using ST5-RL. The rhamnolipids were able to remove TPH from the sample by the mechanism of solubilisation. Also, the biocidal effect of RL and RL-washings (from the soil treatment) at 10, 100 and 1000 ppm was studied by carrying out cytotoxicity test on breast cancer …
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Towards Understanding the Genetic Basis of Virulence in Pseudomonas aeruginosa
… of gelatinase and caseinase, and production of rhamnolipids and siderophores). Photographic images of phenotyping plates were analysed using machine learning analysis methods. Across all six phenotypes studied, I identified more than 500 hits in 449 genes that resulted in a change in phenotype …
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Metabolomic insights into Pseudomonas aeruginosa behavior, secretome, and biofilm development using mass spectrometry imaging
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-08-01
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Bioprospección de microorganismos presentes en hidrocarburos para determinar el potencial productor de biosurfactantes y determinación de equipos principales para su producción.
En este trabajo se presenta el proceso de bioprospección de microorganismos nativos en tres muestras puntuales de hidrocarburos de los departamentos del Casanare y Boyacá, enfocado a la búsqueda de Pseudomonas sp., por ser un grupo reportado en otros países para la producción de ramnolípidos y …
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Secondary ion mass spectrometry imaging of surface-bound microbial communities
As we move into the heart of the 21st century we are finally beginning to understand the extent of microbial influence over everyday life. Truth be told, we humans are but guests on a planet ruled by a largely unseen, and often undiscovered, microbial population. In order to understand how the …