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Showing 1 to 20 of 51 for “"RfC"”.
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Combat stress reaction and morale in RFC/RAF aircrew 1914-1918
… examined and analysed the operations of the RFC/RAF over the Western Front from 1014-1918 with the aim of establishing the incidence of aircrew failure for nervous disorders. The factors affecting the psychological and psychiatric reactions of aircrew to combat have been examined. The …
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A Repeated Forced-Choice Lineup Procedure: Examining the Impact on Child and Adult Eyewitnesses
… the impact of using a repeated force-choice (RFC) lineup procedure with child and adult eyewitnesses. The RFC procedure divides the identification task into a series of exhaustive binary comparisons (i.e., round-robin design) and, in doing so, provides information about (a) who the witness …
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Recruiting and training the Royal Flying Corps. Finding and preparing the men who would fight Britain’s first war in the air
… neglected aspects of the Royal Flying Corps (RFC) during the First World War: recruitment and training. The study will examine who the RFC recruited for roles both in the air and on the ground. It will explore how the force's makeup changed as the war progressed, why such changes occurred, …
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Low-Power Wireless Sensor Node with Edge Computing for Pig Behavior Classifications
… solution, in which a Random Forest Classifier (RFC) is trained and implemented into WSNs. The implementation of RFC on WSNs does not save power, but the RFC predicts animal behavior such that WSNs can adaptively adjust the data sampling frequency to reduce power consumption. In addition, WSNs …
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Development of Natural Filling Cystometer and Comparison with Conventional Cystometry
… the conventional retrograde filling cystometry (RFC) on spinal cord injured patients with neurogenic bladder. Three persons (two spinal cord injuries and one stroke) with voiding symptoms were recruited for testing the NFC. As urine filled inside the bladder, the transurethral and rectal …
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The proton-coupled folate transporter: biology and therapeutic applications to cancer
… cells is achieved by the reduced folate carrier (RFC) and proton-coupled folate transporter (PCFT). As PCFT is a folate-proton symporter with an acidic pH optimum, PCFT may provide a mechanism for targeting cytotoxic antifolates to tumors, based on their acidic microenvironments. To establish the …
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Comparative Studies of Processivity Clamp Loader ATP Site Function
… inactivation of γ complex. Replication factor C (RFC) loads the processivity clamp, proliferating cell nuclear antigen (PCNA), onto DNA. ATP binding to RFC activates a γ-phosphate sensor in ATP site C that promotes DNA association by RFC-PCNA. DNA binding to the RFC-PCNA complex then triggers the …
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Single-molecule and ensemble studies of DNA replication system
… studying the clamp (PCNA) and the clamp loader (RFC) from the mesophilic archaeon Methanosarcina acetivorans, and then moved to the single-molecule level trying to reconstitute the DNA replication machinery protein by protein. In the first study, by developing a real-time fluorescence assay, we …
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Utilidad de la ecocardiografía de estrés dipiridamol con media reserva de flujo coronario y reserva contráctil en el diagnóstico de enfermedad vascular del injerto en pacientes trasplantados cardiacos
… izquierdo y la reserva de flujo coronario (RFC) en la arteria descendente anterior (DA) durante la ecocardiografía de estrés con dipiridamol (DiSE) ha sido propuesta por la Asociación Europea de Ecocardiografía como un método viable y preciso para el diagnóstico de la enfermedad. coronaria. …
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Eficacia de la radiofrecuencia convencional vs pulsada sobre el dolor y la funcionalidad en los pacientes con gonartrosis moderada-severa remitidos a la unidad del dolor
… sus dos modalidades, radiofrecuencia continua (RFC) y radiofrecuencia pulsada (RFP), de los nervios geniculares que inervan la cápsula articular de la rodilla pueden ser efectivos para aliviar el dolor, mejorar la discapacidad y la calidad de vida. A diferencia del RFC que produce lesión …
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Clamp loading on the leading strand during DNA replication and initial reconstitution of sister chromatid cohesion establishment
… for this regulation. The clamp loader Rfc1-RFC is essential for PCNA loading to support DNA replication, with an alternative clamp loader, Ctf18-RFC, instead important in many genomic stability maintenance processes. However, our understanding of PCNA loading during DNA replication is …
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New roles of Rac-GEFs in Neutrophils and in Glucose Homeostasis
… our Rac activity FRET reporter mouse strain (RFC) (Johnsson, Dai et al. 2014), crossed to mice deficient in the Rac-GEFs P-Rex1/Vav1, DOCK2 or Tiam1. I demonstrated that Rac activity is increased in RFC Tiam1–/– neutrophils adhering to integrin ligands, which may explain the increased …
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Synthesis of novel 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as selective and potent anti-tumor agents
… are transported via reduced folate career (RFC) as well as Folate receptors (FRs) and/or Proton coupled folate transporter (PCFT). Because RFC is ubiquitous in the human body, the dose limiting toxicity is unavoidable for an antifolate if it is a substrate for RFC. To circumvent this …
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Molecular and Biochemical Analyses of a Three-Subunit Euryarchaeal Clamp Loader Complex
… pentameric protein, replication factor C (RFC), functions as the clamp loader, which installs the sliding clamp onto primer-template junction of DNA in an ATP-dependent manner. The critical clamp loader acts as molecular switch from distributive to processive DNA synthesis. Here, we …
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Design and Synthesis of Pyrimidine Based Fused Heterocyclics in the Potential Treatment of Cancer and Opportunistic Infection
… cells that include the reduced folate carrier (RFC), folate receptors (FRs) α and β, and the proton-coupled folate transporter (PCFT). Among several targeting strategies for cancer cells, selectively targeting through PCFT and FRs, over RFC have been successfully investigated. To avoid …
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Target Based Design and Synthesis of Fused Pyrimidines in the Potential Treatment of Cancer and Opportunistic Infection
… folates through reduced folate carrier (RFC), Proton-Coupled Folate Transporter (PCFT) and/or Folate receptors (FR). Among several targeting strategies for cancer cells, selectively targeting through PCFT and FRs, over RFC have been successfully investigated. The next valid step in the …
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Autenticación de microservicios basados en OAuth
… se encuentra recopilado en el documento RFC-6819. En el presente trabajo, se procede a planificar, diseñar, desarrollar y ejecutar un entorno construido en base a una arquitectura de microservicios que hagan uso del protocolo de autorización de OAuth 2.0. De la misma manera, se analiza y …
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Facilitating software reuse by structuring the SPS user interface management system's software library according to programmer mental models
… inheritance-tree (D IT) and response-for-class (RFC) (Lei, 1991, 1993). These two metrics had been found by Lei to correlate with the ease of maintenance of software. It was conjectured that they might also be useful in the study of mental model methods for software. Finally, student and …
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Algorithm and Design Tool Development of Sizing a Stand-Alone Pv/Wt/Electrolyzer/Hydrogen/Fuelcell Power Generation System for Electricity Supply Under Weatherrelated Uncertainty Considerations and Thermo-Fluid Effects
… air, pumped hydro (PHS), regenerative fuel cell (RFC), etc.), and by using a method that can forecast the historical weather data (called WYGM from now onward) for the sake of obtaining any statistical data that can map the potential at any site of interests. Moreover, since it is impractical to …
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The Operations of FNMA in the Secondary Mortgage Market
… of funds available for home financing .|The RFC Mortgage Company was created in 1935 by the Reconstruction Finance Corporation to finance mortgages that could not be financed reasonably from private sources and also to assist in the development of the mortgage market by its purchases of …
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