Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 215 for “"Rev"”.
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Characterization of HIV-1 Rev mutants
The HIV Rev protein has the ability to bind tubulin heterodimers and depolymerize microtubules (MTs) in vitro (Watts et al. 2000). These interactions may account for MT defects observed in HIV infected cells or cells that over-express Rev. Watts et al. hypothesized Rev interacts with MTs by a …
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The Rev-mediated Dimerization of HIV RRE RNA
The HIV-1 Regulator of Virion Expression (Rev) a regulatory protein which is critical for the late-phase development of the Human Immunodeficiency Virus-1 (HIV-1). During early-phase development of HIV-1, Rev accumulates in the cytoplasm and is transported into the nucleus through interactions with …
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The Rev-mediated Dimerization of HIV RRE RNA
The HIV-1 Regulator of Virion Expression (Rev) a regulatory protein which is critical for the late-phase development of the Human Immunodeficiency Virus-1 (HIV-1). During early-phase development of HIV-1, Rev accumulates in the cytoplasm and is transported into the nucleus through interactions with …
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Structural and biophysical studies of HIV-1 Rev protein
Rev is a key HIV-1 virus regulatory protein, which exports the unspliced and partially\r\nspliced viral mRNA out of the nucleus, thereby inducing the switch from the early phase\r\nto the late phase of the viral replication cycle. Because it is prone to form filaments at\r\nvery low concentration, …
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Principles of Catechetical Instruction According to Rev. Peter C. Yorke
Abstract Not Available
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Binding Determinants of HIV-1 REV RNA to the Pokeweed Antiviral Protein
… PAP has also been shown to depurinate the ORF of Rev RNA of HIV-1 in vivo without causing toxicity. The sequence and structure of Rev RNA that PAP interacts is identified and compared to the sarcin/ricin loop in order to describe the importance of RNA structure for PAP specificity. My results show …
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Epigenomic and Transcriptional Regulation of Hepatic Metabolism by REV-ERB and Hdac3
… HDAC3 corresponds to the expression pattern of REV-ERBα, an important component of the circadian clock. REV-ERBα colocalizes with HDAC3 near genes regulating lipid metabolism, and deletion of HDAC3 or Rev-erbα in mouse liver causes hepatic steatosis. Thus, genomic recruitment of HDAC3 by …
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Analysis of Protein and RNA Interactions of the HIV-1 rev Protein
<p>The HIV-1 Rev protein enters the nucleus via it’s nuclear localization sequence/RNA binding domain and interacts with a ≈234 nt region of viral RNA, termed the Rev Response Element (RRE), which is located in the <em>env</em> region of unspliced and singly-spliced HIV-1 mRNA. The Rev nuclear …
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Enhancement of anti-HIV-1 Ribozyme Activities by Rev Binding and Multimerization
… dependent on <em>env</em> gene expression. HIV-1 Rev protein binds to a higher ordered RNA structure within the <em>env</em> transcript termed the Rev Binding Element (RBE). In anti-HIV gene therapy employing ribozymes to increase the co-localization of anti- HIV ribozymes with target HIV mRNAs, …
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The Three Parts of Babylon : Teaching a Historicist Interpretation of the Leopardlike, Lamblike and Scarlet Beasts (Rev 13 and 16:19 as Reflected in Rev 17) Based upon the Douglas Waterhouse Construct
… which the biblical three parts of Babylon (Rev 16:19) and the visual imagery of apocalyptic Babylon (Rev 13 and 17) might be taught effectively within the historicist tradition. This study was designed to present a teaching strategy based upon the historicist apocalyptic three-part construct …
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Molecular Studies involving the Rev Protein of Caprine Arthritis Encephalitis Virus and Visna Virus.
… and <em>env</em>) and two regulatory genes (<em>rev</em> and <em>tat</em>). The Rev protein regulates Gag, Pol and Env expression by transporting their mRNAs to the cytoplasm by binding to the RRE (Rev Response Element) found on their mRNAs. Previous studies have indicated that Rev may be toxic …
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Structure determination of an HIV-1 RRE RNA-Rev peptide complex by NMR spectroscopy
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1996.
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The Rev. Francis Close and the Foundation of the Training Institution at Cheltenham 1845-78
… college was primarily the work of one man, the Rev. Francis Close who was the incumbent of Cheltenham between 1824 - 1856. He played a key role at every stage including the ini tial period when the first proposal was made in 1845. Contrary to previous accounts it was not founded there in …
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UNDERSTANDING HEPATIC REV-ERBa INTERACTING PARTNERS AS IT PEAKS AND TROUGHS THROUGH THE CIRCADIAN DAY
… and exciting data about the nuclear receptors REV-ERBa and REV-ERBREV-ERBs are interesting proteins to understand because they play important roles in the circadian clock and in the regulation of metabolism on a variety of tissues. Understanding how a factor can link both the clock and …
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The Background and Meaning of the Image of the Beast in Rev. 13:14, 15
… of the motif of the image of the beast in Rev 13:14, 15, in order to answer the problem of the author’s intended meaning of the image of the beast to his first century Greco-Roman readers.</p> <p>Method</p> <p>There are six steps necessary to accomplish the task of this dissertation. These …
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An examination of the life and career of Rev William McGill (1732-1807): controversial Ayr theologian
… controversy in Ayrshire, centred around the Rev William McGill (1732-1807), the associate minister to William Dalrymple (1723-1814) of the Old Kirk in Ayr. McGill was principally accused of holding ‘Socinian’ views, particularly in his Practical Essay on the Death of Jesus Christ (1786) which …
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Targeting Alternative Conformational States of the HIV-1 Rev Response Element Stem IIB using Small Molecules
… RNA in drug discovery as therapeutics. The HIV-1 Rev response element (RRE) RNA which is a known drug target mediates the export of incompletely-spliced viral RNA to express viral proteins required for HIV-1 replication and spread. Rev protein first recognizes the purine-rich region on RRE stem …
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Magic and the supernatural in eighteenth-century Wales: the world of the Rev. Edmund Jones (1702-1793)
The Rev. Edmund Jones (1702-1793), the 'Old Prophet' of the Transh, Pontypool, is a fascinating character for many reasons, not least of which is his writing on apparitions, spirits, fairies, and magic in his Geographical, Historical, and Religious Account of the Parish of Aberystruth (1779) and …
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The "Second Reformation" in Ireland, 1798-1861: case study of Rev. Robert Winning and the Kingscourt District.
… Reformation’ in Ireland through a case study of Rev. Robert Winning and the Kingscourt District with which he was closely associated. The Kingscourt District defines the geographical parameters of this study; the period between 1798 and 1861 its chronological limits. The early date, 1798, is …
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