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Showing 1 to 4 of 4 for “"Retinol dehydrogenase"”.
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Establishment of retinoic acid gradients in the early development of Xenopus laevis
… (ZNS). Die Synthese von RA aus Vitamin A (Retinol) läuft in zwei Schritten ab, wobei die zweite Reaktion- katalysiert von Retinal-Dehydrogenasen (RALDHs)- lange als entscheidend für die gewebsspezifische Produktion von RA im Embryo angesehen wurde. Das kürzlich identifizierte Xenopus …
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RDH10 is Necessary for Initial Vagal Neural Crest Cell Contribution to Embryonic Gastrointestinal Tract Development
Retinol dehydrogenase 10 (RDH10) catalyzes the first oxidative step in the metabolism of vitamin A to its active form retinoic acid (RA). Insufficient or excess RA can result in various congenital abnormalities, such as Hirschsprung disease (HSCR). In HSCR, neurons are absent from variable lengths …
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Regulation of morphogen signalling during neural patterning in the Xenopus embryo
… differentiation. Third, we present Xenopus retinol dehydrogenase-10 (XRDH10) as a critical enzyme for embryonic vitamin A metabolism and retinoic acid (RA) synthesis in the developing embryo. We show that XRDH10, which oxidizes vitamin A to retinal, is transcriptionally inhibited by RA, …
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GENOMIC AND MICROBIOME ANALYSIS TO IMPROVE FILLET YIELD AND QUALITY TRAITS IN RAINBOW TROUT
… (e.g., β,β-carotene 15,15-dioxygenase, retinol dehydrogenase), myoglobin regulation (ATP5F1B), and structural maintenance of muscle tissue (klh41b, COL28A1, CTSK). RNA-Seq further highlighted genes involved in lipid/carotenoid metabolism, ribosomal function, mitochondrial activity, and …