Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Retinoic acid-inducible gene 1 (RIG-I)"”.
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MyD88-Mediated Signaling in Protective Immunity against an Attenuated West Nile Virus Infection
… macrophages, which were mediated by TLR7 and retinoic acid-inducible gene 1 (RIG-I) signaling pathways. Thus, a defective viral life cycle during NS4B-P38G mutant infection in human monocytic and macrophage cells leads to more potent cell intrinsic innate cytokine responses. In summary, my …
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The Cellular Mirna, Mir-190, is Upregulated in Type I Ebv Latency by Ebers and Modulates Cellular Mrnas involved in Cell Survival and Viral Reactivation
… I, and miR-190 upregulation is due to viral gene expression. Lentiviral overexpression systems were used to overexpress miR-190 and a microarray of gene expression revealed candidate miR-190 targets, including: TP53INP1 and NR4A3. The modulation of these targets by miR-190 was confirmed …
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Single molecule investigation of antiviral signaling
Retinoic acid-inducible gene 1 (RIG-I) plays a major role in antiviral innate immunity by detecting cytoplasmic viral RNA and triggering the pathway that leads to transcriptional activation of type I interferon (IFN). Type I IFN induces a large set of genes called interferon-stimulated genes (ISGs) …