Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Retinal nerve fibre layer"”.
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Characteristic distribution of peripapillary retinal nerve fibre layer oedema in acute methanol-induced optic neuropathy
… a characteristic distribution of peripapillary retinal nerve fibre layer oedema in acute methanol-induced optic neuropathy (Me-ION). Methods: This retrospective case series study included four adult patients with acute Me-ION treated at Groote Schuur hospital in Cape Town during the national …
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Machine Learning Algorithms for Improved Glaucoma Diagnosis
… condition characterized by damage to the optic nerve and retinal nerve fibre layer, and results in visual field defects afflicting the visual function. Highly specific and sensitive diagnostic tests able to detect the clinically significant glaucomatous changes in the structure of the nerve …
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En face OCT imaging for the assessment of glaucoma
… OCT developments enabled direct assessment of retinal nerve fibre bundle (RNFB) reflectance in en face OCT images. The technique has considerable potential in the assessment of glaucoma, yet it has limited clinical usability due to an incomplete understanding of RNFB features in healthy and …
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Knowledge Mining In The Clinical Assessment Of Glaucoma
… characterized by structural changes in the optic nerve head (ONH) and retinal nerve fibre layer (RNFL) that can be evaluated by various retinal-imaging techniques such as scanning laser polarimetry and optical coherence tomography (OCT). The structural damage can lead to functional damage in the …
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Structural Integrity of Eyes Diagnosed with Amblyopia. The measurement of retinal structure in amblyopia using Optical Coherence Tomography.
… study was to establish the prevalence of subtle retinal/optic nerve head defects in eyes diagnosed with amblyopia, to distinguish between possible explanations for the origin of such defects and to investigate the relationship between quantitative measures of retinal structure, retinal nerve …
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Understanding the genetics and function of complex human retinal phenotypes
… nervous system, the retina has a complex and layered structure, with each layer performing a vital step in the signal transformation process. Changes in the morphology of this structure are often a consequence of disease, which can affect the function of the eye. Better understanding of the …
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Bioenergetic neuroprotection in experimental glaucoma
… neuropathy and associated degeneration of the retinal ganglion cells (RGCs). It is a leading cause of blindness worldwide. Although the pathogenesis of the most common variant, primary open-angle glaucoma, remains poorly understood, there is considerable evidence that energy insufficiency plays …
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Relationships between subtle ocular changes and microvascular complications in people with type 2 diabetes
… develop analytical methods of quantifying retinal and choroidal biomarkers of structure and/or function, including novel biomarkers such as choroid thickness, choriocapillaris perfusion, and retinal capillary perfusion, to ensure collection of high-quality data for aims 1) and 2). Methods: …
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Characterizing neurodegeneration, neuroinflammation and immunological status through multimodal strategies in type 1 diabetes mellitus and relapsing-remitting multiple sclerosis
… and optical coherence tomography (OCT) for retinal nerve fibre layer (RNFL) thickness. Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (GFAP) were also measured. Both patient groups exhibited cognitive and mood disturbances and significantly elevated sNfL levels, …