Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Retinal Microvasculature"”.
-
The retinal microvasculature as an early indicator of chronic disease risk in older populations
… been suggested that the measurement of retinal blood vessel parameters could provide an increased understanding of chronic systemic diseases with a vascular component. This easy, non-invasive imaging modality provides an indication of microvascular health that may reflect ongoing changes …
-
Role of pericytes in the barrier task
… and controlling tissue homeostasis. The blood-retinal barrier (BRB) is a blood-ocular barrier system, made up of an inner and an outer barrier. BRB is located in the retinal microvasculature and include the microvascular endothelium. The role of the BRB is to control molecule trafficking: ion, …
-
Investigation of the role of Glil+ cells in retinal angiogenesis and fibrosis.
… lesion development. Cell survival assays of retinal pigment epithelial and microvascular endothelial cells in the presence of TGFβ2 together with/without Gli1 inhibitor GANT61 were utilised to interrogate the role of Gli1 in mesenchymal transition.<br/><br/>Results: Expression of Gli1-Tomato …
-
Investigation of novel biomarkers associated with renal disease
… a body of work examining associations between retinal biomarkers (retinal microvascular parameters [RVP] and retinal layer thickness measurements) and measures of renal function and damage (estimated glomerular filtration rate and urinary albumin to creatinine ratio). Retinal biomarkers have …
-
Relationships between subtle ocular changes and microvascular complications in people with type 2 diabetes
… develop analytical methods of quantifying retinal and choroidal biomarkers of structure and/or function, including novel biomarkers such as choroid thickness, choriocapillaris perfusion, and retinal capillary perfusion, to ensure collection of high-quality data for aims 1) and 2). Methods: …
-
Characterisation of endothelial cell metabolic plasticity and vascular remodelling in the retina
… severe vision loss. A key component cell of the retinal neurovascular unit is the vascular endothelium, which is significantly impacted by the diabetic milieu. It has now been established that the endothelium relies on glycolytic metabolism predominantly for ATP generation, however the degree of …