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Showing 1 to 20 of 117 for “"Resveratrol"”.
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Synthesis of Resveratrol Ester Derivatives
… project was to synthesize derivatives of transresveratrol. In order for resveratrol to be activated and used by the body it needs to bind to Human Serum Albumin (HSA), a protein in blood plasma. The derivatives were synthesized to improve the ability of resveratrol to enter cells as well as …
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Synthesis of a Resveratrol Glycinate Derivative.
<p>Recently, the compound resveratrol has had media attention as an anti carcinogen. However, the bioavailability of resveratrol is low in the human system due to its hydrophobic nature. Therefore, it must be administered in high dosages to be effective. A plethora of derivatives have been …
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Synthesis of Resveratrol Esters and Aliphatic Acids.
<p>Resveratrol (RV) is a naturally occurring phytoalexin of the stilbenoid family produced by some plant species, and present in grape skin, peanuts, and red wine. It has been found to exhibit anti-cancer, anti-inflammatory, anti-viral, anti-aging, cardio protective, and anti-oxidant properties. …
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Anti-Obesity Effects of Adipose-Targeting Resveratrol Nanocarriers
… efficient approach for combating obesity. Trans-resveratrol (R) has an anti-obesity potential via inducing adipose stromal stem cells (ASC) differentiation into beige adipocytes in WAT. But its low levels of aqueous solubility, bioavailability, and targeting specificity limit its application in …
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Resveratrol Analogs: Potential Chemopreventive Agents in Breast Cancer
… occurring well studied antioxidants like resveratrol (Res), resveratrol analogs (TIMBD and HPIMBD) and Vitamin C. Resveratrol has been shown to reduce primary tumor growth of xenografts in a nude mouse model. But its clinical applications in prevention of breast cancer are limited because …
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Investigation of resveratrol metabolism using liquid chromatography-mass spectrometry.
Investigation of resveratrol metabolism using liquid chromatography-mass spectrometry.
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Synthesis of Resveratrol Ester Derivatives Using Selective Enzymatic Hydrolysis.
<p>Resveratrol, a naturally derived stilbene, is an interesting compound mostly talked about recently because for its anti-cancer properties. Unfortunately it has some shortcomings due to its low bioavailability and low solubility in water. For this reason, my research is to overcome resveratrol's …
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PHARMACOKINETICS OF RESVERATROL, ITS MONOCONJUGATES AND ITS TRIMETHOXY ANALOG TMS
Resveratrol (RES) has been associated with numerous pharmacological effects. Yet its pharmacokinetics is not clearly understood. It is known to get extensively metabolized into its sulfated and glucuronidated metabolites and has very low circulating RES concentrations in plasma. Although the …
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Studies towards Selective Synthesis of Resveratrol-based Oligomeric Natural Products
… of the past and present efforts in the field of resveratrol-based oligomeric natural product synthesis. Both biosynthetic approaches and stepwise synthetic approaches are discussed to present the current level of understanding regarding the controlled synthesis of these molecules in order to …
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Resveratrol Nanostructured Lipid Carrier for targeted delivery to breast cancer
… of drug and targeting of desired tissue. Resveratrol (RES) is a chemotherapeutic drug limited by its physiochemical properties (i.e. poor solubility and bioavailability), encapsulation into NLCs is potentially viable solution to the aforementioned issues. Aim: The main aim of the present …
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Stabilization of resveratrol through microencapsulation and incorporation into food products
… healthful ingredients. This research utilized resveratrol, a polyphenol found in red grapes and wine, as a model compound which encapsulation was applied in order to overcome the light instability and bitterness of the compound. Resveratrol was encapsulated within a protein matrix through spray …
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The supramolecular modification of trans-resveratrol and related antioxidant molecules
The naturally occurring phytoalexin trans-Resveratrol (RES) is known to be a powerful antioxidant and is used as a nutraceutical. It is considered to be one of the factors contributing to the beneficial effects of red wine. The phenolic hydroxycinnamic acids caffeic acid (CAF), ferulic acid (FA), …
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PULMONARY DELIVERY OF RESVERATROL-LOADED NANOCOMPOSITE MICROPARTICLES TO TREAT LUNG CANCER
… need to be investigated. Towards this goal, resveratrol loaded polymeric nanoparticles (NPs) formulated into nanocomposite microparticles (NCMPs) using L-leucine and chitosan were developed for the pulmonary delivery via dry powder inhalation. Resveratrol was loaded into NPs of poly(glycerol …
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Estudio de la Complejación del resveratrol por diferentes tipos de ciclodextrinas
… se plantea el estudio de la complejación del resveratrol con diferentes tipos de CDs. Por los beneficios que puede aportar el resveratrol a la salud, y las escasas cantidades y fuentes en las que se encuentra, sería interesante poder elaborar alimentos funcionales que lo contengan. Así, para …
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Resveratrol Regulates IGF- II and Cathepsin D in Breast Cancer Cells
… of cancer among women in the US. Phytoestrogen resveratrol (RS V) has been described as a potential ehemotherapeutic agent, but has been associated with breast cancer cell growth and cell death. RSV binds to estrogen receptors (ER) and functions as a mixed estrogen agonist/antagonist. The …
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Synthesis of Ester Derivatives of Resveratrol as Potential Anti-Cancer Drugs
<p>Resveratrol is a naturally occurring phytoalexin of the stilbene family produced by various plants in response to stress, UV radiation, and fungal attack. It is primarily found in peanuts, berries, grape skin, and red wine. Resveratrol has been found to exhibit anti-cancer, anti-inflammatory, …
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Synergistically active curcumin resveratrol solid lipid nanoparticles for treatment of melanoma
Poorly soluble polyphenols such as curcumin and resveratrol have shown significant potential in the treatment of melanoma due to their multifarious roles in its pathogenesis. Furthermore, the combination of curcumin and resveratrol was found to demonstrate synergistic effects in other cancers; …
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Resveratrol: therapeutic role in metabolic and reproductive function in obese broodmares
Resveratrol, a naturally-occurring phytoestrogenic stilbene derivative, has been shown to elicit shifts in physiology of obese animals consuming a high calorie or ad libitum diet toward that of lean counterparts. This study was designed to evaluate effects of oral resveratrol supplementation on …
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