Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Responsive Hydrogel"”.
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Design, fabrication, and application of stimuli-responsive hydrogel actuators
In this thesis, the topics around stimuli-responsive hydrogel actuators were discussed. In each project, a specially designed, stimuli-responsive, hydrogel was fabricated. By initiating a corresponding stimuli, swell-deswell changes were triggered within the hydrogels, and certain mechanical …
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Control of surface structure and properties of responsive hydrogel interfaces via electrostatic interactions
Hydrogels are primary candidates for applications in soft robotics, biomedical devices, and tissue engineering due to their biocompatibility, extremely low coefficients of friction, and potential for a variety of responsive behaviors.[1] Their biphasic nature and viscoelastic network results in a …
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Synthesis and Applications of Novel Responsive Materials
This thesis describes the synthesis of responsive organic polymers which show potential for use in a variety of applications. A series of pyridine terminated m-phenylene ethynylene oligomers were synthesized. When trans-dichlorobis(acetonitrile)palladium was added to a solution of these oligomers, …
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Synthesis of reactive and stimuli-responsive polymer thin films by initiated chemical vapor deposition and their sensor applications
Stimuli-responsive polymer thin films provide the ability to control the interaction of a surface with its environment. Synthetic techniques with fine compositional control are required to engineer specific responses to stimuli. Initiated chemical vapor deposition (iCVD) is a novel vacuum …
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Metal-polymer nanoparticulate systems for externally-controlled delivery
… consisting of gold nanorods and temperature-responsive hydrogel nanoparticulates were investigated for use in externally-controlled drug delivery systems. Several different thermo-responsive hydrogels including poly(N-isopropyl acrylamide) (PNIPAAm) and poly(N-isopropryl acrylamide-co-acrylic …
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Strategies for incorporating functional block copolymers into polyelectrolyte multilayer coatings
This thesis explores the creation of thin film responsive hydrogel coatings via Layer-by Layer assembly (LbL) of temperature (T) responsive block copolymer - polyelectrolyte multilayers (PEMs). First, the LbL conditions that allow for temperature driven, large, reversible swelling transitions of …
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Synthetic Degradable Polymer Systems for Drug Delivery
… joint. Chapter 2 describes the study of a thermo-responsive injectable hydrogel for the controlled release of GSK3787, a potential disease-modifying therapeutic for OA. The hydrogel was prepared from methacrylate-capped poly(caprolactone-co-lactide)- poly(ethylene …
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Novel carriers for oral delivery of hemophiliac factor IX
… convenient prophylactic treatment. Complexation hydrogels have been engineered to protect biologics from the harsh environment of the GI tract and deliver them to the small intestine for absorption. We have successfully developed pH-responsive hydrogel networks based on poly(methacrylic …
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PHOTO-GUIDED SHAPE TRANSFORMATION OF COMPOSITE HYDROGEL SHEETS
Shape-changing hydrogel material has numerous potential applications in biomimetics, soft robotics, biomedicine, etc. Light as a clean energy source can be remotely delivered to material with high spatial and temporal resolution, which brings new controllability to shape-transformation of hydrogel …
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Polysaccharides in Amyloid Aggregation and Hydrogel Mechanics: Insights from Molecular Modeling
… reported. The first case study considered a pH-responsive hydrogel system composed of the polysaccharide chitosan, and an anionic surfactant. Experiments showed that the hydrogels had contrasting mechanical properties at the two pH extremes. Our simulations, which spanned atomistic, …
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Development of light actuated chemical delivery platform on a 2-D array of micropore structure
… In this paper, we demonstrate a light-controlled hydrogel platform that can be used for localized chemical delivery in a high spatial resolution. By utilizing the photothermal behavior of graphene-hydrogel composites confined within micron-sized fluidic channels, patterned light illumination …