Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 78 for “"Respiratory distress syndrome"”.
-
Endotype Discovery in Acute Respiratory Distress Syndrome
Endotype Discovery in Acute Respiratory Distress Syndrome Dr Romit Samanta Acute respiratory distress syndrome (ARDS) affects 10% of critical care patients and is characterised by acute refractory hypoxaemia and bilateral pulmonary infiltrates on thoracic imaging. Mortality from severe ARDS is …
-
Biochemical aspects of the idiopathic respiratory distress syndrome of the newborn
This study was undertaken primarily to investigate the plasma protein system in infants with IRDS, as compared with healthy premature infants, as it had previously been reported that the plasma protein concentration in affected infants was abnormally low. It was attempted further to establish …
-
Identification of novel coding single nucleotide polymorphisms associated with acute respiratory distress syndrome
… in complex genetic conditions such as acute respiratory distress syndrome (ARDS). To identify disease-causing variants in ARDS patients, whole-exome sequencing was performed on 96 patient DNA samples from the National Heart, Lung and Blood Institute's ARDS Network (ARDSnet). By comparing …
-
The effects of mechanical ventilation on the development of Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS) is a severe lung illness characterized by inflammation and fluid accumulation in the respiratory system. Historically, ARDS and other forms of respiratory failure have been treated using mechanical ventilation to help maintain gas exchange in the lungs. …
-
The role of inflammasomes in a murine model of acute respiratory distress syndrome (ARDS)
Acute respiratory distress syndrome is rapid pulmonary inflammation that can cause organ failure which is commonly caused by sepsis, severe pneumonia and trauma. ARDS has become one of the top research priorities since the SARS-CoV-2 outbreak in 2020. From injury to damaged tissue repair, cell …
-
Human mesenchymal stromal cell regulation of pulmonary macrophage populations in the Acute Respiratory Distress Syndrome
The Acute Respiratory Distress Syndrome (ARDS) is a devastating clinical disorder characterised by excessive inflammation in the alveolar compartment resulting in oedema of the airspaces due to loss of integrity in the alveolar epithelial-endothelial barrier. ARDS is associated with high mortality …
-
Incidence and Pathogenesis of Acute Lung Injury and the Acute Respiratory Distress Syndrome in Humans
… injury (ALI) and it’s more severe form, acute respiratory distress syndrome (ARDS), are conditions characterised by neutrophilic pulmonary inflammation, refractory hypoxaemia and diffuse alveolar damage. This work reports on the first UK based prospective study of the incidence and longer term …
-
Exogenous surfactant transport through the pulmonary airways : improving surfactant replacement therapy for neonatal respiratory distress syndrome
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1996.
-
Effects of hypercapnic acidosis on the primary cells relevant to acute respiratory distress syndrome pathophysiology and the therapeutic potential of Mesenchymal Stem Cells
Acute Respiratory Distress Syndrome (ARDS) is an inflammatory disorder in which the integrity of the alveolar epithelial-capillary endothelial barrier breaks down, facilitating the accumulation of a protein-rich oedema fluid within the alveoli. Despite years of clinical trials, no effective …
-
Outcomes of patients with COVID-19 Acute Respiratory Distress Syndrome requiring Invasive Mechanical Ventilation admitted to an Intensive Care Unit in South Africa
Background Up to 30% of patients with COVID-19 pneumonia may require ICU admission or mechanical ventilation [Guan et al., 2020; Huang et al., 2020]. Data from low- and middle-income countries for COVID-19 ARDS are limited. Groote Schuur Hospital in Cape Town, South Africa expanded its ICU service …
-
The respiratory distress syndrome of the newborn : studies of blood gases and acid/base balance with the object of formulating principles of treatment
Respiratory failure accounts for a large, if not the largest, percentage of deaths during the first 48 hours of life. During the last ten years a great deal of research has been devoted to this early respiratory failure. The syndrome has been known by different names at different times; hyaline …
-
Surfactant for the treatment of respiratory distress syndrome in very low birth weight infants at a level 2 hospital: a descriptive retrospective cohort study – safety and efficacy
Abstract: Background and rationale: Respiratory Distress Syndrome (RDS) is common in pre-term infants and is related to immaturity of the lungs. Surfactant therapy is now being widely used outside of tertiary neonatal centres. The purpose of this study is to describe the demographics and the …
-
Characterization of the dynamic behavior of lung surfactant and its components
Lung surfactant is essential to respiratory function. Surfactant dysfunction in adult respiratory distress syndrome (ARDS) is associated with an increase in the minimum surface tension achieved on compression which can result in alveolar collapse and decreased lung compliance. Knowledge of the …
-
Der Sauerstoffverbrauch der Lunge (VO2pulm) bei Patienten mit Acute Lung Injury (ALI) und Acute Respiratory Distress Syndrome (ARDS) unter mechanischer Beatmung und PEEP-Variation, gemessen als VO2-Differenz zwischen indirekter Kalorimetrie und Berechnung über das inverse Fick´ sche Prinzip
Bei Patienten mit einem akuten Lungenversagen (ALI oder ARDS) ist der Sauerstoffverbrauch der Lunge (VO2pulm) durch pathophysiologische Prozesse insbesondere die Ausbildung von Atelektasen stark beeinträchtigt. Aufgrund der Annahme, dass eine Steigerung der Anzahl ventilierter Lungenareale zu einer …
-
A Patient-Specific Multiscale Model of Mechanical Ventilation of COVID-19-afflicted Lungs
Coronavirus disease-2019 (COVID-19) is a respiratory disease that caused a worldwide pandemic and, in some cases, manifests as an acute respiratory distress syndrome. Severe cases of COVID-19 are often treated with mechanical ventilation, which has a high risk of causing ventilator-induced lung …
-
Long-term impacts of antenatal corticosteroid exposure and preterm birth
… preterm birth after an initial course decreased respiratory distress syndrome and other serious infant outcomes compared with the initial course alone. No benefits or harms were identified at mid-childhood. We re-analysed data from the first randomised, placebo-controlled trial of antenatal …
-
Pacifier stiffness alters the dynamics of the suck central pattern generator
… born prematurely with and without a history of respiratory distress syndrome. Three types of Soothie™ silicone pacifiers used in the NICU were tested for materials stiffness, revealing the Super Soothie™ is 7 times stiffer. No significant between-subjects effects were found for the healthy …
Page 1 of 4